A New Method to Detect Variants of SARS-CoV-2 Using Reverse Transcription Loop-Mediated Isothermal Amplification Combined with a Bioluminescent Assay in Real Time (RT-LAMP-BART)

A New Method to Detect Variants of SARS-CoV-2 Using Reverse Transcription Loop-Mediated Isothermal Amplification Combined with a Bioluminescent Assay in Real Time (RT-LAMP-BART)

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), of which there are several variants. The three major variants (Alpha, Delta, and Omicron) carry the N501Y, L452R, and Q493R/Q498R mutations, respectively, in the <i>S</i> gene....

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Bibliographic Details
Main Authors: Takahiro Iijima, Jun Sakai, Dai Kanamori, Shinnosuke Ando, Tsutomu Nomura, Laurence Tisi, Paul E. Kilgore, Neil Percy, Hikaru Kohase, Satoshi Hayakawa, Shigefumi Maesaki, Tomonori Hoshino, Mitsuko Seki
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
SARS-CoV-2
variants of concern
spike protein
loop-mediated isothermal amplification
Online Access:https://www.mdpi.com/1422-0067/24/13/10698

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