Cardiological Syndrome X: Diagnosis and Intensive Care

Objective: to study the efficacy of the atypical neuroleptic sulpiride in the complex intensive therapy for cardialgic syndrome X (CSX).Subjects and methods. Sixty-six patients with CSX were randomly divided into 2 groups comparable by clinical and history data. Group 1 including 33 patients receive...

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Main Authors: Yu. V. Shirokikh, S. I. Kuznetsov, N. V. Shapovalova
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2007-08-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/973
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author Yu. V. Shirokikh
S. I. Kuznetsov
N. V. Shapovalova
author_facet Yu. V. Shirokikh
S. I. Kuznetsov
N. V. Shapovalova
author_sort Yu. V. Shirokikh
collection DOAJ
description Objective: to study the efficacy of the atypical neuroleptic sulpiride in the complex intensive therapy for cardialgic syndrome X (CSX).Subjects and methods. Sixty-six patients with CSX were randomly divided into 2 groups comparable by clinical and history data. Group 1 including 33 patients received traditional intensive antianginal therapy. Group 2 patients were additionally given the atypical neuroleptic sulpiride. The duration of therapy was 4 weeks; thereafter the impact of the therapy performed was evaluated by the time course of changes in anginal symptoms, the frequency of attacks a day, the adaptive capacities of the cardiovascular system, and psychoneurological status.Results. In Group 2 patients taking sulpiri-de in complex therapy, there were more reductions in the number of anginal attacks, their severity and duration. Pain syndrome relief was achieved in the earlier periods. Sulpiride exerted a positive effect on the patients’ psychoneurological status, which made itself evident in the abolishment of the anxious and depressive manifestations of the disease.Conclusion. Reduced symptoms and improved adaptive capacities of the cardiovascular system in CSX patients treated with sulfide leads to the conclusion that the drug used in complex and intensive therapy for CSX is a current effective psychocorrect-ing agent that is well tolerated and safe, which promotes the improvement of final treatment Results.
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spelling doaj.art-d629b9d34add48808cb7d3940d333da32023-03-13T09:32:47ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102007-08-0134838710.15360/1813-9779-2007-4-83-87973Cardiological Syndrome X: Diagnosis and Intensive CareYu. V. Shirokikh0S. I. Kuznetsov1N. V. Shapovalova2Воронежская государственная медицинская академия им. Н. Н. Бурденко Федерального агентства по здравоохранению и социальному развитию, Воронеж Кафедра анестезиологии и реаниматологии Института последипломного медицинского образования Государственного образовательного учреждения высшего профессионального образования, ГУЗ Воронежская областная клиническая больница №1Воронежская государственная медицинская академия им. Н. Н. Бурденко Федерального агентства по здравоохранению и социальному развитию, Воронеж Кафедра анестезиологии и реаниматологии Института последипломного медицинского образования Государственного образовательного учреждения высшего профессионального образования, ГУЗ Воронежская областная клиническая больница №1Воронежская государственная медицинская академия им. Н. Н. Бурденко Федерального агентства по здравоохранению и социальному развитию, Воронеж Кафедра анестезиологии и реаниматологии Института последипломного медицинского образования Государственного образовательного учреждения высшего профессионального образования, ГУЗ Воронежская областная клиническая больница №1Objective: to study the efficacy of the atypical neuroleptic sulpiride in the complex intensive therapy for cardialgic syndrome X (CSX).Subjects and methods. Sixty-six patients with CSX were randomly divided into 2 groups comparable by clinical and history data. Group 1 including 33 patients received traditional intensive antianginal therapy. Group 2 patients were additionally given the atypical neuroleptic sulpiride. The duration of therapy was 4 weeks; thereafter the impact of the therapy performed was evaluated by the time course of changes in anginal symptoms, the frequency of attacks a day, the adaptive capacities of the cardiovascular system, and psychoneurological status.Results. In Group 2 patients taking sulpiri-de in complex therapy, there were more reductions in the number of anginal attacks, their severity and duration. Pain syndrome relief was achieved in the earlier periods. Sulpiride exerted a positive effect on the patients’ psychoneurological status, which made itself evident in the abolishment of the anxious and depressive manifestations of the disease.Conclusion. Reduced symptoms and improved adaptive capacities of the cardiovascular system in CSX patients treated with sulfide leads to the conclusion that the drug used in complex and intensive therapy for CSX is a current effective psychocorrect-ing agent that is well tolerated and safe, which promotes the improvement of final treatment Results.https://www.reanimatology.com/rmt/article/view/973ишемическая болезнь сердцакардиалгический синдром х
spellingShingle Yu. V. Shirokikh
S. I. Kuznetsov
N. V. Shapovalova
Cardiological Syndrome X: Diagnosis and Intensive Care
Общая реаниматология
ишемическая болезнь сердца
кардиалгический синдром х
title Cardiological Syndrome X: Diagnosis and Intensive Care
title_full Cardiological Syndrome X: Diagnosis and Intensive Care
title_fullStr Cardiological Syndrome X: Diagnosis and Intensive Care
title_full_unstemmed Cardiological Syndrome X: Diagnosis and Intensive Care
title_short Cardiological Syndrome X: Diagnosis and Intensive Care
title_sort cardiological syndrome x diagnosis and intensive care
topic ишемическая болезнь сердца
кардиалгический синдром х
url https://www.reanimatology.com/rmt/article/view/973
work_keys_str_mv AT yuvshirokikh cardiologicalsyndromexdiagnosisandintensivecare
AT sikuznetsov cardiologicalsyndromexdiagnosisandintensivecare
AT nvshapovalova cardiologicalsyndromexdiagnosisandintensivecare