Outcome assessment in acute pancreatitis patients

Early diagnosis and severity evaluation in patients with acute pancreatitis (AP) are very important due to its potential morbidity and mortality. Several clinical, laboratory, and radiologic factors, and many scoring systems have been proposed for outcome prediction. Although the Ranson and Acute Ph...

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Main Authors: Wei-Sin Lee, Jee-Fu Huang, Wan-Long Chuang
Format: Article
Language:English
Published: Wiley 2013-09-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X12003051
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author Wei-Sin Lee
Jee-Fu Huang
Wan-Long Chuang
author_facet Wei-Sin Lee
Jee-Fu Huang
Wan-Long Chuang
author_sort Wei-Sin Lee
collection DOAJ
description Early diagnosis and severity evaluation in patients with acute pancreatitis (AP) are very important due to its potential morbidity and mortality. Several clinical, laboratory, and radiologic factors, and many scoring systems have been proposed for outcome prediction. Although the Ranson and Acute Physiology and Chronic Health Evaluation II scoring systems have been widely used for decades, the cumbersome components partly limit their predictability. Recently, the Bedside Index for Severity in AP scoring system and series blood urea nitrogen changes, which are simple and convenient to evaluate within 24 hours after admission, have been validated for accuracy by several large-cohort studies. The presence of organ failure and systemic inflammatory response syndrome are also helpful to evaluate the severity of AP. Herein we review recent advances of the predictive methods for AP to provide an up-to-date perspective on outcome assessment of AP.
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spelling doaj.art-d62a8a3ebe044107a9688daa6a985a572022-12-22T00:55:51ZengWileyKaohsiung Journal of Medical Sciences1607-551X2013-09-0129946947710.1016/j.kjms.2012.10.007Outcome assessment in acute pancreatitis patientsWei-Sin Lee0Jee-Fu Huang1Wan-Long Chuang2Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanDepartment of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung, TaiwanDepartment of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanEarly diagnosis and severity evaluation in patients with acute pancreatitis (AP) are very important due to its potential morbidity and mortality. Several clinical, laboratory, and radiologic factors, and many scoring systems have been proposed for outcome prediction. Although the Ranson and Acute Physiology and Chronic Health Evaluation II scoring systems have been widely used for decades, the cumbersome components partly limit their predictability. Recently, the Bedside Index for Severity in AP scoring system and series blood urea nitrogen changes, which are simple and convenient to evaluate within 24 hours after admission, have been validated for accuracy by several large-cohort studies. The presence of organ failure and systemic inflammatory response syndrome are also helpful to evaluate the severity of AP. Herein we review recent advances of the predictive methods for AP to provide an up-to-date perspective on outcome assessment of AP.http://www.sciencedirect.com/science/article/pii/S1607551X12003051Acute pancreatitisDisease outcomeMortality and morbidityScoring systemsSystemic inflammatory response syndrome
spellingShingle Wei-Sin Lee
Jee-Fu Huang
Wan-Long Chuang
Outcome assessment in acute pancreatitis patients
Kaohsiung Journal of Medical Sciences
Acute pancreatitis
Disease outcome
Mortality and morbidity
Scoring systems
Systemic inflammatory response syndrome
title Outcome assessment in acute pancreatitis patients
title_full Outcome assessment in acute pancreatitis patients
title_fullStr Outcome assessment in acute pancreatitis patients
title_full_unstemmed Outcome assessment in acute pancreatitis patients
title_short Outcome assessment in acute pancreatitis patients
title_sort outcome assessment in acute pancreatitis patients
topic Acute pancreatitis
Disease outcome
Mortality and morbidity
Scoring systems
Systemic inflammatory response syndrome
url http://www.sciencedirect.com/science/article/pii/S1607551X12003051
work_keys_str_mv AT weisinlee outcomeassessmentinacutepancreatitispatients
AT jeefuhuang outcomeassessmentinacutepancreatitispatients
AT wanlongchuang outcomeassessmentinacutepancreatitispatients