Impact of COVID-19 pandemic on retention in care of native and migrant people with HIV in the ICONA cohort
Background: COVID-19 pandemic challenged the UNAIDS 90-90-90 targets. How the COVID-19 pandemic affected HIV retention in care and whether it has disproportionally affected migrant people with HIV (PWH) remained to be investigated. Methods: PWH in ICONA Cohort in follow-up in each of the study perio...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Travel Medicine and Infectious Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S147789392400005X |
| _version_ | 1827317014900768768 |
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| author | Roberta Gagliardini Andrea Giacomelli Giorgio Bozzi Antonella D'Arminio Monforte Alessandro Tavelli Valentina Mazzotta Elena Bruzzesi Adriana Cervo Annalisa Saracino Cristina Mussini Enrico Girardi Alessandro Cozzi-Lepri Andrea Antinori |
| author_facet | Roberta Gagliardini Andrea Giacomelli Giorgio Bozzi Antonella D'Arminio Monforte Alessandro Tavelli Valentina Mazzotta Elena Bruzzesi Adriana Cervo Annalisa Saracino Cristina Mussini Enrico Girardi Alessandro Cozzi-Lepri Andrea Antinori |
| author_sort | Roberta Gagliardini |
| collection | DOAJ |
| description | Background: COVID-19 pandemic challenged the UNAIDS 90-90-90 targets. How the COVID-19 pandemic affected HIV retention in care and whether it has disproportionally affected migrant people with HIV (PWH) remained to be investigated. Methods: PWH in ICONA Cohort in follow-up in each of the study periods were included: 01/09/2019-29/02/2020 (pandemic period) and 01/03/2018-31/08/2018 (historical period, as a control). Risk of temporary loss to follow-up (LTFU, defined as no data recorded for a person for one year) was analyzed by logistic regression, with migrant status as the main exposure variable. Difference in difference (DID) analysis was applied to evaluate the effect of COVID-19 pandemic in the different risk of LTFU between natives and migrants. Results: 8864 (17.1% migrants) and 8071 (16.8% migrants) PWH constituted the pandemic and the historical period population, respectively.Proportion of PWH defined as LTFU in the pandemic period was 10.5% in native and 19.6% in migrant PWH.After controlling for age, sex and geographical location of enrolling site, risk of temporary LTFU was higher for migrants than native PWH [adjusted odds ratio 1.85 (95%CI 1.54–2.22)] in pandemic period. In PWH contributing to both periods, LTFU was 9.0% (95% CI 8.3–9.8) in natives vs 17.0% (95% CI 14.7–19.4) in migrants during the pandemic. Instead, LTFU was 1.2% (95%CI 0.9, 1.5) in natives vs 2.2% (95% CI 1.3–3.1) in migrants during the historical period, with a resulting DID of 7.0% (95% CI 4.4–9.6). Conclusions: A greater proportion of LTFU in migrant PWH was observed in both periods, which remained unaltered over time. Interventions to reduce LTFU of migrants are necessary. |
| first_indexed | 2024-03-08T03:13:11Z |
| format | Article |
| id | doaj.art-d62b2d8bd9fa4359a1c7305bfe98ba54 |
| institution | Directory Open Access Journal |
| issn | 1873-0442 |
| language | English |
| last_indexed | 2024-04-24T23:25:20Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Travel Medicine and Infectious Disease |
| spelling | doaj.art-d62b2d8bd9fa4359a1c7305bfe98ba542024-03-16T05:08:11ZengElsevierTravel Medicine and Infectious Disease1873-04422024-03-0158102691Impact of COVID-19 pandemic on retention in care of native and migrant people with HIV in the ICONA cohortRoberta Gagliardini0Andrea Giacomelli1Giorgio Bozzi2Antonella D'Arminio Monforte3Alessandro Tavelli4Valentina Mazzotta5Elena Bruzzesi6Adriana Cervo7Annalisa Saracino8Cristina Mussini9Enrico Girardi10Alessandro Cozzi-Lepri11Andrea Antinori12Clinical and Research Infectious Diseases Department, National Institute of Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, ItalyIII Infectious Disease Unit, ASST-Fatebenefratelli Sacco, Milan, ItalyInfectious Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, ItalyIcona Foundation, Milan, Italy; Corresponding author. Antonella d’Arminio Monforte, Icona Foundation, Milan, Italy.Icona Foundation, Milan, ItalyClinical and Research Infectious Diseases Department, National Institute of Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, ItalyUO Malattie Infettive, IRCCS Ospedale San Raffaele, ItalyDivision of Infectious Diseases, University of Modena, Modena, ItalyClinic of Infectious Diseases, University Hospital, University of Bari, Bari, ItalyDivision of Infectious Diseases, University of Modena, Modena, ItalyScientific Direction, National Institute for Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, ItalyCentre for Clinical Research, Epidemiology, Modelling and Evaluation (CREME), Institute for Global Health, University College London, London, UKClinical and Research Infectious Diseases Department, National Institute of Infectious Diseases Lazzaro Spallanzani IRCCS, Rome, ItalyBackground: COVID-19 pandemic challenged the UNAIDS 90-90-90 targets. How the COVID-19 pandemic affected HIV retention in care and whether it has disproportionally affected migrant people with HIV (PWH) remained to be investigated. Methods: PWH in ICONA Cohort in follow-up in each of the study periods were included: 01/09/2019-29/02/2020 (pandemic period) and 01/03/2018-31/08/2018 (historical period, as a control). Risk of temporary loss to follow-up (LTFU, defined as no data recorded for a person for one year) was analyzed by logistic regression, with migrant status as the main exposure variable. Difference in difference (DID) analysis was applied to evaluate the effect of COVID-19 pandemic in the different risk of LTFU between natives and migrants. Results: 8864 (17.1% migrants) and 8071 (16.8% migrants) PWH constituted the pandemic and the historical period population, respectively.Proportion of PWH defined as LTFU in the pandemic period was 10.5% in native and 19.6% in migrant PWH.After controlling for age, sex and geographical location of enrolling site, risk of temporary LTFU was higher for migrants than native PWH [adjusted odds ratio 1.85 (95%CI 1.54–2.22)] in pandemic period. In PWH contributing to both periods, LTFU was 9.0% (95% CI 8.3–9.8) in natives vs 17.0% (95% CI 14.7–19.4) in migrants during the pandemic. Instead, LTFU was 1.2% (95%CI 0.9, 1.5) in natives vs 2.2% (95% CI 1.3–3.1) in migrants during the historical period, with a resulting DID of 7.0% (95% CI 4.4–9.6). Conclusions: A greater proportion of LTFU in migrant PWH was observed in both periods, which remained unaltered over time. Interventions to reduce LTFU of migrants are necessary.http://www.sciencedirect.com/science/article/pii/S147789392400005XSARS-CoV-2Retention in careLoss to follow-up |
| spellingShingle | Roberta Gagliardini Andrea Giacomelli Giorgio Bozzi Antonella D'Arminio Monforte Alessandro Tavelli Valentina Mazzotta Elena Bruzzesi Adriana Cervo Annalisa Saracino Cristina Mussini Enrico Girardi Alessandro Cozzi-Lepri Andrea Antinori Impact of COVID-19 pandemic on retention in care of native and migrant people with HIV in the ICONA cohort Travel Medicine and Infectious Disease SARS-CoV-2 Retention in care Loss to follow-up |
| title | Impact of COVID-19 pandemic on retention in care of native and migrant people with HIV in the ICONA cohort |
| title_full | Impact of COVID-19 pandemic on retention in care of native and migrant people with HIV in the ICONA cohort |
| title_fullStr | Impact of COVID-19 pandemic on retention in care of native and migrant people with HIV in the ICONA cohort |
| title_full_unstemmed | Impact of COVID-19 pandemic on retention in care of native and migrant people with HIV in the ICONA cohort |
| title_short | Impact of COVID-19 pandemic on retention in care of native and migrant people with HIV in the ICONA cohort |
| title_sort | impact of covid 19 pandemic on retention in care of native and migrant people with hiv in the icona cohort |
| topic | SARS-CoV-2 Retention in care Loss to follow-up |
| url | http://www.sciencedirect.com/science/article/pii/S147789392400005X |
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