The Combination of Δ<sup>9</sup>-Tetrahydrocannabinol and Cannabidiol Suppresses Mitochondrial Respiration of Human Glioblastoma Cells via Downregulation of Specific Respiratory Chain Proteins

The Combination of Δ<sup>9</sup>-Tetrahydrocannabinol and Cannabidiol Suppresses Mitochondrial Respiration of Human Glioblastoma Cells via Downregulation of Specific Respiratory Chain Proteins

Phytocannabinoids represent a promising approach in glioblastoma therapy. Previous work has shown that a combined treatment of glioblastoma cells with submaximal effective concentrations of psychoactive Δ<sup>9</sup>-tetrahydrocannabinol (THC) and non-psychoactive cannabidiol (CBD) great...

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Bibliographic Details
Main Authors: Anne Rupprecht, Ulrike Theisen, Franziska Wendt, Marcus Frank, Burkhard Hinz
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
cannabinoids
Δ<sup>9</sup>-tetrahydrocannabinol
cannabidiol
glioblastoma cells
mitochondria
oxygen consumption rate
Online Access:https://www.mdpi.com/2072-6694/14/13/3129

Internet

https://www.mdpi.com/2072-6694/14/13/3129

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