Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives
In this study appropriate hydrazide compounds, furan-2-carboxylic acidhydrazide (1) and phenylacetic acid hydrazide (2) were converted into 1,4-substitutedthiosemicarbazides 4a-e and 5a-e and 4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The 1,4-substituted thiosemicarbazides...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2004-03-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/9/4/204/ |
| _version_ | 1819266881214742528 |
|---|---|
| author | A. Demirdağ A. Cansız M. Koparır |
| author_facet | A. Demirdağ A. Cansız M. Koparır |
| author_sort | A. Demirdağ |
| collection | DOAJ |
| description | In this study appropriate hydrazide compounds, furan-2-carboxylic acidhydrazide (1) and phenylacetic acid hydrazide (2) were converted into 1,4-substitutedthiosemicarbazides 4a-e and 5a-e and 4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The 1,4-substituted thiosemicarbazides were then converted into5-(furan-2-yl or benzyl)-4-(aryl)-4H-1,2,4-triazole-3-thiols 8a-e and 9a-e. In addition, theazomethines 11a-d and 12a-d were prepared from the corresponding arylaldehydes and the4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The structures of allthe synthesized compounds were confirmed by elemental analyses, IR, 1H-NMR and13 C-NMR spectra. |
| first_indexed | 2024-12-23T21:08:19Z |
| format | Article |
| id | doaj.art-d62f1d43032e4310858ca4541a766352 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-23T21:08:19Z |
| publishDate | 2004-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-d62f1d43032e4310858ca4541a7663522022-12-21T17:31:09ZengMDPI AGMolecules1420-30492004-03-019420421210.3390/90400204Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol DerivativesA. DemirdağA. CansızM. KoparırIn this study appropriate hydrazide compounds, furan-2-carboxylic acidhydrazide (1) and phenylacetic acid hydrazide (2) were converted into 1,4-substitutedthiosemicarbazides 4a-e and 5a-e and 4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The 1,4-substituted thiosemicarbazides were then converted into5-(furan-2-yl or benzyl)-4-(aryl)-4H-1,2,4-triazole-3-thiols 8a-e and 9a-e. In addition, theazomethines 11a-d and 12a-d were prepared from the corresponding arylaldehydes and the4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The structures of allthe synthesized compounds were confirmed by elemental analyses, IR, 1H-NMR and13 C-NMR spectra.http://www.mdpi.com/1420-3049/9/4/204/4H-124-triazole-3-thiolsazomethinesthiosemicarbazides. |
| spellingShingle | A. Demirdağ A. Cansız M. Koparır Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives Molecules 4H-1 2 4-triazole-3-thiols azomethines thiosemicarbazides. |
| title | Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives |
| title_full | Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives |
| title_fullStr | Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives |
| title_full_unstemmed | Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives |
| title_short | Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives |
| title_sort | synthesis of some new 4 5 substituted 4h 1 2 4 triazole 3 thiol derivatives |
| topic | 4H-1 2 4-triazole-3-thiols azomethines thiosemicarbazides. |
| url | http://www.mdpi.com/1420-3049/9/4/204/ |
| work_keys_str_mv | AT ademirdaaay synthesisofsomenew45substituted4h124triazole3thiolderivatives AT acansaaz synthesisofsomenew45substituted4h124triazole3thiolderivatives AT mkoparaar synthesisofsomenew45substituted4h124triazole3thiolderivatives |