Erythroleukemia: Classification
Abstract Acute erythroid leukemia (AEL) is a rare (2%–5%) form of acute myeloid leukemia (AML). Molecular alterations found in AEL resemble those of other AMLs. We report a classification of AELs in three major classes, with different prognosis and some specific features such as a tendency to mutual...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-05-01
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| Series: | eJHaem |
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| Online Access: | https://doi.org/10.1002/jha2.676 |
| _version_ | 1797740067751460864 |
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| author | Nathalie Cervera Arnaud Guille José Adélaïde Marie‐Anne Hospital Sylvain Garciaz Marie‐Joelle Mozziconacci Norbert Vey Véronique Gelsi‐Boyer Daniel Birnbaum |
| author_facet | Nathalie Cervera Arnaud Guille José Adélaïde Marie‐Anne Hospital Sylvain Garciaz Marie‐Joelle Mozziconacci Norbert Vey Véronique Gelsi‐Boyer Daniel Birnbaum |
| author_sort | Nathalie Cervera |
| collection | DOAJ |
| description | Abstract Acute erythroid leukemia (AEL) is a rare (2%–5%) form of acute myeloid leukemia (AML). Molecular alterations found in AEL resemble those of other AMLs. We report a classification of AELs in three major classes, with different prognosis and some specific features such as a tendency to mutual exclusion of mutations in epigenetic regulators and signaling genes. |
| first_indexed | 2024-03-12T14:07:06Z |
| format | Article |
| id | doaj.art-d6312bdd72cb46629c506d098c5d8cc2 |
| institution | Directory Open Access Journal |
| issn | 2688-6146 |
| language | English |
| last_indexed | 2024-03-12T14:07:06Z |
| publishDate | 2023-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | eJHaem |
| spelling | doaj.art-d6312bdd72cb46629c506d098c5d8cc22023-08-21T14:05:59ZengWileyeJHaem2688-61462023-05-014245045310.1002/jha2.676Erythroleukemia: ClassificationNathalie Cervera0Arnaud Guille1José Adélaïde2Marie‐Anne Hospital3Sylvain Garciaz4Marie‐Joelle Mozziconacci5Norbert Vey6Véronique Gelsi‐Boyer7Daniel Birnbaum8Laboratoire d'Oncologie Prédictive Centre de Recherche en Cancérologie de Marseille (CRCM) Institut Paoli‐Calmettes INSERM UMR 1068 CNRS UMR725 Aix‐Marseille Université Marseille FranceLaboratoire d'Oncologie Prédictive Centre de Recherche en Cancérologie de Marseille (CRCM) Institut Paoli‐Calmettes INSERM UMR 1068 CNRS UMR725 Aix‐Marseille Université Marseille FranceLaboratoire d'Oncologie Prédictive Centre de Recherche en Cancérologie de Marseille (CRCM) Institut Paoli‐Calmettes INSERM UMR 1068 CNRS UMR725 Aix‐Marseille Université Marseille FranceDépartement d'Hématologie Institut Paoli‐Calmettes Marseille FranceDépartement d'Hématologie Institut Paoli‐Calmettes Marseille FranceDépartement de BioPathologie Institut Paoli‐Calmettes Marseille FranceDépartement d'Hématologie Institut Paoli‐Calmettes Marseille FranceLaboratoire d'Oncologie Prédictive Centre de Recherche en Cancérologie de Marseille (CRCM) Institut Paoli‐Calmettes INSERM UMR 1068 CNRS UMR725 Aix‐Marseille Université Marseille FranceLaboratoire d'Oncologie Prédictive Centre de Recherche en Cancérologie de Marseille (CRCM) Institut Paoli‐Calmettes INSERM UMR 1068 CNRS UMR725 Aix‐Marseille Université Marseille FranceAbstract Acute erythroid leukemia (AEL) is a rare (2%–5%) form of acute myeloid leukemia (AML). Molecular alterations found in AEL resemble those of other AMLs. We report a classification of AELs in three major classes, with different prognosis and some specific features such as a tendency to mutual exclusion of mutations in epigenetic regulators and signaling genes.https://doi.org/10.1002/jha2.676acute erythroid leukemiamolecular classificationmutationsTP53 |
| spellingShingle | Nathalie Cervera Arnaud Guille José Adélaïde Marie‐Anne Hospital Sylvain Garciaz Marie‐Joelle Mozziconacci Norbert Vey Véronique Gelsi‐Boyer Daniel Birnbaum Erythroleukemia: Classification eJHaem acute erythroid leukemia molecular classification mutations TP53 |
| title | Erythroleukemia: Classification |
| title_full | Erythroleukemia: Classification |
| title_fullStr | Erythroleukemia: Classification |
| title_full_unstemmed | Erythroleukemia: Classification |
| title_short | Erythroleukemia: Classification |
| title_sort | erythroleukemia classification |
| topic | acute erythroid leukemia molecular classification mutations TP53 |
| url | https://doi.org/10.1002/jha2.676 |
| work_keys_str_mv | AT nathaliecervera erythroleukemiaclassification AT arnaudguille erythroleukemiaclassification AT joseadelaide erythroleukemiaclassification AT marieannehospital erythroleukemiaclassification AT sylvaingarciaz erythroleukemiaclassification AT mariejoellemozziconacci erythroleukemiaclassification AT norbertvey erythroleukemiaclassification AT veroniquegelsiboyer erythroleukemiaclassification AT danielbirnbaum erythroleukemiaclassification |