| Summary: | Because clinical studies on diagnosis, management, prevention, and many other aspects of pregnancy and breastfeeding during COVID-19 have improved significantly since the beginning of the pandemic, a substantial amount of prior knowledge has changed, and previous publications may no longer be applicable. In addition, to reduce maternal, fetal, and neonatal morbidity and mortality in the event of future pandemics, vaccination recommendations in pregnancy must be made early. This review of the literature seeks to offer a comprehensive update on the mutual effects of pregnancy and COVID-19 infection, debate current issues based on the most recent discoveries, and identify existing knowledge gaps. Emerging studies indicate significant risks associated with SARS-CoV-2 infection during pregnancy, including preeclampsia, intrauterine growth restriction, preterm birth, and the risk of birth malformations. Vaccination against COVID-19 is advised for women who are pregnant, trying to become pregnant, breastfeeding, or who may become pregnant in the future. Vaccination during pregnancy is associated with the transmission of SARS-CoV-2 antibodies to the fetus. Additional clinical trials should investigate long-term consequences, results, the safety of vaccinations, and the influence of the pandemic on the health of pregnant women.
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