Interaction between SNCA, LRRK2 and GAK increases susceptibility to Parkinson's disease in a Chinese population

Interaction between SNCA, LRRK2 and GAK increases susceptibility to Parkinson's disease in a Chinese population

PD is a complex disease, and may result from gene–gene and gene–environment interactions. There are limited studies on gene–gene interactions in PD. We and others have previously shown that SNCA rs356219, LRRK2 (rs2046932 and rs7304279) and GAK (rs1564282) are risk factors in sporadic PD. Since the...

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Bibliographic Details
Main Authors: Wen-Juan Yu, Lan Cheng, Nan-Nan Li, Ling Wang, Eng-King Tan, Rong Peng
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:eNeurologicalSci
Subjects:
Parkinson's disease
SNCA
LRRK2
GAK
MDR
Gene–gene interaction
Online Access:http://www.sciencedirect.com/science/article/pii/S2405650215000039

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