Efficiency of Enzymatic Debridement in the Healing Process of Chronic Wounds in Small Animal Practice

Skin wounds are a common presentation in small animal practice. These wounds may be acute or chronic with a complicated healing process. An important aspect of the healing of wounds is debridement which may be carried out by surgical, autolytic, mechanical or enzymatic methods. The debridement metho...

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Main Authors: Hamilton L., Kožár M.
Format: Article
Language:English
Published: Sciendo 2017-03-01
Series:Folia Veterinaria
Subjects:
Online Access:https://doi.org/10.1515/fv-2017-0006
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author Hamilton L.
Kožár M.
author_facet Hamilton L.
Kožár M.
author_sort Hamilton L.
collection DOAJ
description Skin wounds are a common presentation in small animal practice. These wounds may be acute or chronic with a complicated healing process. An important aspect of the healing of wounds is debridement which may be carried out by surgical, autolytic, mechanical or enzymatic methods. The debridement method is chosen according to the individual skin defect and influenced by factors such as wound size and location, the age of the wound, and the presence of infection or exudate. Enzymatic debridement is a method that is not commonly used in veterinary practice, and involves the use of enzyme preparations to remove necrotic tissue from a wound. The aim of this study was to investigate the effects of the enzymatic ointment collagenase as a method of debridement, and its effect on the macroscopic appearance of chronic skin wounds in cats and dogs. We observed that the application of Iruxol Mono directly to the wound changes the progress of the healing process, with no obvious adverse effects. The time of healing of chronic wounds was decreased and healthy granulation tissue was developed within a couple of days after application of the ointment. Enzymatic debridement appears to be a promising method of debridement for use in chronic wounds, and should be considered in cases where more conventional methods of debridement are ineffective or unsuitable.
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spelling doaj.art-d63e27dcaab445dc9329572d4433276c2022-12-21T22:37:07ZengSciendoFolia Veterinaria2453-78372017-03-01611384210.1515/fv-2017-0006fv-2017-0006Efficiency of Enzymatic Debridement in the Healing Process of Chronic Wounds in Small Animal PracticeHamilton L.0Kožár M.1University of Veterinary Medicine and Pharmacy, Komenského 73, 04181 Košice, SlovakiaUniversity of Veterinary Medicine and Pharmacy, Komenského 73, 04181 Košice, SlovakiaSkin wounds are a common presentation in small animal practice. These wounds may be acute or chronic with a complicated healing process. An important aspect of the healing of wounds is debridement which may be carried out by surgical, autolytic, mechanical or enzymatic methods. The debridement method is chosen according to the individual skin defect and influenced by factors such as wound size and location, the age of the wound, and the presence of infection or exudate. Enzymatic debridement is a method that is not commonly used in veterinary practice, and involves the use of enzyme preparations to remove necrotic tissue from a wound. The aim of this study was to investigate the effects of the enzymatic ointment collagenase as a method of debridement, and its effect on the macroscopic appearance of chronic skin wounds in cats and dogs. We observed that the application of Iruxol Mono directly to the wound changes the progress of the healing process, with no obvious adverse effects. The time of healing of chronic wounds was decreased and healthy granulation tissue was developed within a couple of days after application of the ointment. Enzymatic debridement appears to be a promising method of debridement for use in chronic wounds, and should be considered in cases where more conventional methods of debridement are ineffective or unsuitable.https://doi.org/10.1515/fv-2017-0006collagenasechronic woundsdebridementenzymes
spellingShingle Hamilton L.
Kožár M.
Efficiency of Enzymatic Debridement in the Healing Process of Chronic Wounds in Small Animal Practice
Folia Veterinaria
collagenase
chronic wounds
debridement
enzymes
title Efficiency of Enzymatic Debridement in the Healing Process of Chronic Wounds in Small Animal Practice
title_full Efficiency of Enzymatic Debridement in the Healing Process of Chronic Wounds in Small Animal Practice
title_fullStr Efficiency of Enzymatic Debridement in the Healing Process of Chronic Wounds in Small Animal Practice
title_full_unstemmed Efficiency of Enzymatic Debridement in the Healing Process of Chronic Wounds in Small Animal Practice
title_short Efficiency of Enzymatic Debridement in the Healing Process of Chronic Wounds in Small Animal Practice
title_sort efficiency of enzymatic debridement in the healing process of chronic wounds in small animal practice
topic collagenase
chronic wounds
debridement
enzymes
url https://doi.org/10.1515/fv-2017-0006
work_keys_str_mv AT hamiltonl efficiencyofenzymaticdebridementinthehealingprocessofchronicwoundsinsmallanimalpractice
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