Middle bile duct cancer with portal vein tumor thrombus

<p>Abstract</p> <p>Background</p> <p>Tumor thrombus in the portal vein is a common complication of hepatocellular carcinoma, but an extremely rare complication of common bile duct cancer.</p> <p>Case presentation</p> <p>A 78-year-old woman was re...

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Main Authors: Murakami Koji, Fujimori Takahiro, Tomita Shigeki, Iso Yukihiro, Shimoda Mitsugi, Sawada Tokihiko, Kubota Keiichi
Format: Article
Language:English
Published: BMC 2008-05-01
Series:World Journal of Surgical Oncology
Online Access:http://www.wjso.com/content/6/1/48
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author Murakami Koji
Fujimori Takahiro
Tomita Shigeki
Iso Yukihiro
Shimoda Mitsugi
Sawada Tokihiko
Kubota Keiichi
author_facet Murakami Koji
Fujimori Takahiro
Tomita Shigeki
Iso Yukihiro
Shimoda Mitsugi
Sawada Tokihiko
Kubota Keiichi
author_sort Murakami Koji
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Tumor thrombus in the portal vein is a common complication of hepatocellular carcinoma, but an extremely rare complication of common bile duct cancer.</p> <p>Case presentation</p> <p>A 78-year-old woman was referred to our department because of jaundice. Laboratory data showed severe liver dysfunction with high serum levels of total bilirubin and CA19-9. Computed tomography showed lesions in the middle bile duct and main portal vein. FDG PET scan and 3D imaging showed hot spots in the same location as those revealed by CT. Under a diagnosis of middle bile duct cancer with portal vein tumor thrombus, the patient underwent surgery. At laparotomy, the main tumor was found to be located in the middle bile duct with a tumor thrombus, 2 cm in diameter, in the main portal vein. The patient underwent pancreatoduodenectomy with thrombectomy. Histological examination showed that this thrombus had the same histological features as those of the main bile duct cancer (poorly differentiated adenocarcinoma). The postoperative course was uneventful and the patient is doing well without any signs of recurrence 18 months after surgery.</p> <p>Conclusion</p> <p>To our knowledge, this is the first report of successful resection of middle bile duct cancer with portal vein tumor thrombus.</p>
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spelling doaj.art-d6406ecc98c44593a50bc3d5aa7044be2022-12-22T02:55:13ZengBMCWorld Journal of Surgical Oncology1477-78192008-05-01614810.1186/1477-7819-6-48Middle bile duct cancer with portal vein tumor thrombusMurakami KojiFujimori TakahiroTomita ShigekiIso YukihiroShimoda MitsugiSawada TokihikoKubota Keiichi<p>Abstract</p> <p>Background</p> <p>Tumor thrombus in the portal vein is a common complication of hepatocellular carcinoma, but an extremely rare complication of common bile duct cancer.</p> <p>Case presentation</p> <p>A 78-year-old woman was referred to our department because of jaundice. Laboratory data showed severe liver dysfunction with high serum levels of total bilirubin and CA19-9. Computed tomography showed lesions in the middle bile duct and main portal vein. FDG PET scan and 3D imaging showed hot spots in the same location as those revealed by CT. Under a diagnosis of middle bile duct cancer with portal vein tumor thrombus, the patient underwent surgery. At laparotomy, the main tumor was found to be located in the middle bile duct with a tumor thrombus, 2 cm in diameter, in the main portal vein. The patient underwent pancreatoduodenectomy with thrombectomy. Histological examination showed that this thrombus had the same histological features as those of the main bile duct cancer (poorly differentiated adenocarcinoma). The postoperative course was uneventful and the patient is doing well without any signs of recurrence 18 months after surgery.</p> <p>Conclusion</p> <p>To our knowledge, this is the first report of successful resection of middle bile duct cancer with portal vein tumor thrombus.</p>http://www.wjso.com/content/6/1/48
spellingShingle Murakami Koji
Fujimori Takahiro
Tomita Shigeki
Iso Yukihiro
Shimoda Mitsugi
Sawada Tokihiko
Kubota Keiichi
Middle bile duct cancer with portal vein tumor thrombus
World Journal of Surgical Oncology
title Middle bile duct cancer with portal vein tumor thrombus
title_full Middle bile duct cancer with portal vein tumor thrombus
title_fullStr Middle bile duct cancer with portal vein tumor thrombus
title_full_unstemmed Middle bile duct cancer with portal vein tumor thrombus
title_short Middle bile duct cancer with portal vein tumor thrombus
title_sort middle bile duct cancer with portal vein tumor thrombus
url http://www.wjso.com/content/6/1/48
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AT fujimoritakahiro middlebileductcancerwithportalveintumorthrombus
AT tomitashigeki middlebileductcancerwithportalveintumorthrombus
AT isoyukihiro middlebileductcancerwithportalveintumorthrombus
AT shimodamitsugi middlebileductcancerwithportalveintumorthrombus
AT sawadatokihiko middlebileductcancerwithportalveintumorthrombus
AT kubotakeiichi middlebileductcancerwithportalveintumorthrombus