Comparative studies on biophysical interactions between 4-dicyanomethylene-2,6-dimethyl-4H-pyran (DDP) with bovine serum albumin (BSA) and human serum albumin (HSA) via photophysical approaches and molecular docking techniques

Comparative studies on biophysical interactions between 4-dicyanomethylene-2,6-dimethyl-4H-pyran (DDP) with bovine serum albumin (BSA) and human serum albumin (HSA) via photophysical approaches and molecular docking techniques

Photophysical studies of 4-Dicyanomethylene-2,6-Dimethyl-4H-Pyran (DDP) dye with globular proteins, Human Serum Albumin (HSA) and Bovine Serum Albumin (BSA) were carried out in aqueous solution. An isosbestic point resulted on the addition of serum albumins, which signifies a complex or an equilibri...

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Bibliographic Details
Main Authors: Thamarai Selvan Ramachandran, Shoba Gunasekaran, Sangeetha Murugan Sreedevi, Seba Merin Vinod, Kumaran Rajendran, Tamizhdurai Perumal, Alanazi Amer M., Ganesh P.-S.
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Journal of Saudi Chemical Society
Subjects:
DCM
Serum albumins
Fluorescence enhancement
Quenching
Molecular docking
Hydrogen-bonding and hydrophobic interactions
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610321001691

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