Bacterial Detection Rate and Surgical Outcome in Povidone-Iodine Irrigation After Nasolacrimal Duct Intubation
Sho Ishikawa,1 Takuhei Shoji,1 Norihiro Yamada,2 Kei Shinoda1 1Department of Ophthalmology, Saitama Medical University, Saitama, Japan; 2Department of Ophthalmology, Yokohama City University, Kanagawa, JapanCorrespondence: Sho IshikawaDepartment of Ophthalmology, Saitama Medical University, 38 Moroh...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2020-01-01
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| Series: | Clinical Ophthalmology |
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| Online Access: | https://www.dovepress.com/bacterial-detection-rate-and-surgical-outcome-in-povidone-iodine-irrig-peer-reviewed-article-OPTH |
| _version_ | 1818844103561969664 |
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| author | Ishikawa S Shoji T Yamada N Shinoda K |
| author_facet | Ishikawa S Shoji T Yamada N Shinoda K |
| author_sort | Ishikawa S |
| collection | DOAJ |
| description | Sho Ishikawa,1 Takuhei Shoji,1 Norihiro Yamada,2 Kei Shinoda1 1Department of Ophthalmology, Saitama Medical University, Saitama, Japan; 2Department of Ophthalmology, Yokohama City University, Kanagawa, JapanCorrespondence: Sho IshikawaDepartment of Ophthalmology, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, JapanTel +81-4-9276-1250Fax +81-4-9295-8002Email sho_ijp@saitama-med.ac.jpPurpose: In various ophthalmic surgical procedures, 0.25% povidone-iodine (PI) solution is used to prevent infections. This study examined the bacterial colonisation before and after endoscopic nasolacrimal duct intubation irrigated with PI solution and investigated the relationship between bacterial detection and surgical failure.Methods: A retrospective study at Saitama Medical University Hospital. We enrolled 113 patients (33 men, 80 women) who underwent lacrimal intubation surgery between April 2016 and December 2018. Preoperatively, the lacrimal pathways were washed with normal saline solution, which was subsequently cultured. The sites of obstruction in the lacrimal pathway were endoscopically determined, perforated, and intubated. The tubes were afterward either irrigated with 0.25% PI or normal saline every 2 weeks. After 8 weeks, a piece of the removed lacrimal tube was cultured. We characterized the pre- and postoperative bacterial cultures.Results: We enrolled 54 and 52 patients in PI and saline groups (mean age: 69.1± 9.2 and 73.2± 7.2 years), respectively. In the PI group, Staphylococcus epidermidis was less frequently detected postoperatively than preoperatively. S. oralis and Candida parapsilosis were identified more often postoperatively (P=0.02, P=0.01, respectively). The PI group had significantly lower bacterial detection rate than the saline group (P=0.01). However, the surgical failure rates did not differ between groups. In surgical failure patients, the postoperative rate of Pseudomonas aeruginosa was very high (75%).Conclusion: PI reduces the bacterial detection rate but does not improve the surgical success rate. P. aeruginosa is associated with an increased risk of surgical failure.Keywords: nasolacrimal intubation, povidone-iodine, syringing, bacterial population, lacrimal obstructive disease |
| first_indexed | 2024-12-19T05:08:27Z |
| format | Article |
| id | doaj.art-d6434fa4220a4efeb2003129bae5d2b9 |
| institution | Directory Open Access Journal |
| issn | 1177-5483 |
| language | English |
| last_indexed | 2024-12-19T05:08:27Z |
| publishDate | 2020-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-d6434fa4220a4efeb2003129bae5d2b92022-12-21T20:34:51ZengDove Medical PressClinical Ophthalmology1177-54832020-01-01Volume 1420521151357Bacterial Detection Rate and Surgical Outcome in Povidone-Iodine Irrigation After Nasolacrimal Duct IntubationIshikawa SShoji TYamada NShinoda KSho Ishikawa,1 Takuhei Shoji,1 Norihiro Yamada,2 Kei Shinoda1 1Department of Ophthalmology, Saitama Medical University, Saitama, Japan; 2Department of Ophthalmology, Yokohama City University, Kanagawa, JapanCorrespondence: Sho IshikawaDepartment of Ophthalmology, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, JapanTel +81-4-9276-1250Fax +81-4-9295-8002Email sho_ijp@saitama-med.ac.jpPurpose: In various ophthalmic surgical procedures, 0.25% povidone-iodine (PI) solution is used to prevent infections. This study examined the bacterial colonisation before and after endoscopic nasolacrimal duct intubation irrigated with PI solution and investigated the relationship between bacterial detection and surgical failure.Methods: A retrospective study at Saitama Medical University Hospital. We enrolled 113 patients (33 men, 80 women) who underwent lacrimal intubation surgery between April 2016 and December 2018. Preoperatively, the lacrimal pathways were washed with normal saline solution, which was subsequently cultured. The sites of obstruction in the lacrimal pathway were endoscopically determined, perforated, and intubated. The tubes were afterward either irrigated with 0.25% PI or normal saline every 2 weeks. After 8 weeks, a piece of the removed lacrimal tube was cultured. We characterized the pre- and postoperative bacterial cultures.Results: We enrolled 54 and 52 patients in PI and saline groups (mean age: 69.1± 9.2 and 73.2± 7.2 years), respectively. In the PI group, Staphylococcus epidermidis was less frequently detected postoperatively than preoperatively. S. oralis and Candida parapsilosis were identified more often postoperatively (P=0.02, P=0.01, respectively). The PI group had significantly lower bacterial detection rate than the saline group (P=0.01). However, the surgical failure rates did not differ between groups. In surgical failure patients, the postoperative rate of Pseudomonas aeruginosa was very high (75%).Conclusion: PI reduces the bacterial detection rate but does not improve the surgical success rate. P. aeruginosa is associated with an increased risk of surgical failure.Keywords: nasolacrimal intubation, povidone-iodine, syringing, bacterial population, lacrimal obstructive diseasehttps://www.dovepress.com/bacterial-detection-rate-and-surgical-outcome-in-povidone-iodine-irrig-peer-reviewed-article-OPTHnasolacrimal intubationpovidone-iodinesyringingbacterial populationlacrimal obstructive disease |
| spellingShingle | Ishikawa S Shoji T Yamada N Shinoda K Bacterial Detection Rate and Surgical Outcome in Povidone-Iodine Irrigation After Nasolacrimal Duct Intubation Clinical Ophthalmology nasolacrimal intubation povidone-iodine syringing bacterial population lacrimal obstructive disease |
| title | Bacterial Detection Rate and Surgical Outcome in Povidone-Iodine Irrigation After Nasolacrimal Duct Intubation |
| title_full | Bacterial Detection Rate and Surgical Outcome in Povidone-Iodine Irrigation After Nasolacrimal Duct Intubation |
| title_fullStr | Bacterial Detection Rate and Surgical Outcome in Povidone-Iodine Irrigation After Nasolacrimal Duct Intubation |
| title_full_unstemmed | Bacterial Detection Rate and Surgical Outcome in Povidone-Iodine Irrigation After Nasolacrimal Duct Intubation |
| title_short | Bacterial Detection Rate and Surgical Outcome in Povidone-Iodine Irrigation After Nasolacrimal Duct Intubation |
| title_sort | bacterial detection rate and surgical outcome in povidone iodine irrigation after nasolacrimal duct intubation |
| topic | nasolacrimal intubation povidone-iodine syringing bacterial population lacrimal obstructive disease |
| url | https://www.dovepress.com/bacterial-detection-rate-and-surgical-outcome-in-povidone-iodine-irrig-peer-reviewed-article-OPTH |
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