Multi-compartment analysis of the complex gradient-echo signal quantifies myelin breakdown in premanifest Huntington's disease

Multi-compartment analysis of the complex gradient-echo signal quantifies myelin breakdown in premanifest Huntington's disease

White matter (WM) alterations have been identified as a relevant pathological feature of Huntington’s disease (HD). Increasing evidence suggests that WM changes in this disorder are due to alterations in myelin‐associated biological processes. Multi-compartmental analysis of the complex gradient-ech...

Description complète

Détails bibliographiques
Auteurs principaux: Chiara Casella, Elena Kleban, Anne E. Rosser, Elizabeth Coulthard, Hugh Rickards, Fabrizio Fasano, Claudia Metzler-Baddeley, Derek K. Jones
Format: Article
Langue:English
Publié: Elsevier 2021-01-01
Collection:NeuroImage: Clinical
Sujets:
Frequency difference mapping
Three-pool model
Premanifest Huntington’s disease
Myelin
Executive function
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2213158221001029

Internet

http://www.sciencedirect.com/science/article/pii/S2213158221001029

Documents similaires