Rational and semi-rational engineering of cytochrome P450s for biotechnological applications
The cytochrome P450 enzymes are ubiquitous heme-thiolate proteins performing regioselective and stereoselective oxygenation reactions in cellular metabolism. Due to their broad substrate scope and catalytic versatility, P450 enzymes are also attractive candidates for many industrial and biopharmaceu...
Main Authors: | Lian-Hua Xu, Yi-Ling Du |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2018-12-01
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Series: | Synthetic and Systems Biotechnology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405805X18300383 |
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