Stem Cells From Human Exfoliated Deciduous Teeth Alleviate Liver Cirrhosis via Inhibition of Gasdermin D-Executed Hepatocyte Pyroptosis

Stem Cells From Human Exfoliated Deciduous Teeth Alleviate Liver Cirrhosis via Inhibition of Gasdermin D-Executed Hepatocyte Pyroptosis

Liver cirrhosis represents a type of end-stage liver disease with few effective therapies, which was characterized by damaged functional liver tissue due to long-term inflammation. Gasdermin D (GSDMD)-executed programmed necrosis is reported to be involved in inflammation. However, the role of GSDMD...

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Bibliographic Details
Main Authors: Peng Chen, Yi-kun Zhou, Chun-shan Han, Liu-jing Chen, Yi-ming Wang, Zi-meng Zhuang, Shuai Lin, Yan-heng Zhou, Jiu-hui Jiang, Rui-li Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
liver cirrhosis
stem cells from human exfoliated deciduous teeth
NLRP3
GSDMD
pyroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.860225/full

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