High-density lipoprotein cholesterol (HDL-C) in cardiovascular disease: effect of exercise training
Decreases in high-density lipoprotein cholesterol (HDL-C) levels are associated with an increased risk of coronary artery disease (CAD), whereas increased HDL-C levels are related to a decreased risk of CAD and myocardial infarction. Although HDL prevents the oxidation of low-density lipoprotein und...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2016-09-01
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| Series: | Integrative Medicine Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213422016300737 |
| _version_ | 1819297351935721472 |
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| author | Nayoung Ahn Kijin Kim |
| author_facet | Nayoung Ahn Kijin Kim |
| author_sort | Nayoung Ahn |
| collection | DOAJ |
| description | Decreases in high-density lipoprotein cholesterol (HDL-C) levels are associated with an increased risk of coronary artery disease (CAD), whereas increased HDL-C levels are related to a decreased risk of CAD and myocardial infarction. Although HDL prevents the oxidation of low-density lipoprotein under normal conditions, it triggers a structural change, inhibiting antiarteriosclerotic and anti-inflammatory functions, under pathological conditions such as oxidative stress, inflammation, and diabetes. HDL can transform into various structures based on the quantitative reduction and deformation of apolipoprotein A1 and is the primary cause of increased levels of dysfunctional HDL, which can lead to an increased risk of CAD. Therefore, analyzing the structure and components of HDL rather than HDL-C after the application of an exercise training program may be useful for understanding the effects of HDL. |
| first_indexed | 2024-12-24T05:12:38Z |
| format | Article |
| id | doaj.art-d659db41c92d44e081cbbbf60440ed85 |
| institution | Directory Open Access Journal |
| issn | 2213-4220 |
| language | English |
| last_indexed | 2024-12-24T05:12:38Z |
| publishDate | 2016-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Integrative Medicine Research |
| spelling | doaj.art-d659db41c92d44e081cbbbf60440ed852022-12-21T17:13:38ZengElsevierIntegrative Medicine Research2213-42202016-09-015321221510.1016/j.imr.2016.07.001High-density lipoprotein cholesterol (HDL-C) in cardiovascular disease: effect of exercise trainingNayoung AhnKijin KimDecreases in high-density lipoprotein cholesterol (HDL-C) levels are associated with an increased risk of coronary artery disease (CAD), whereas increased HDL-C levels are related to a decreased risk of CAD and myocardial infarction. Although HDL prevents the oxidation of low-density lipoprotein under normal conditions, it triggers a structural change, inhibiting antiarteriosclerotic and anti-inflammatory functions, under pathological conditions such as oxidative stress, inflammation, and diabetes. HDL can transform into various structures based on the quantitative reduction and deformation of apolipoprotein A1 and is the primary cause of increased levels of dysfunctional HDL, which can lead to an increased risk of CAD. Therefore, analyzing the structure and components of HDL rather than HDL-C after the application of an exercise training program may be useful for understanding the effects of HDL.http://www.sciencedirect.com/science/article/pii/S2213422016300737coronary artery diseasedysfunctional HDLexercise traininghigh-density lipoprotein cholesterol (HDL-C) |
| spellingShingle | Nayoung Ahn Kijin Kim High-density lipoprotein cholesterol (HDL-C) in cardiovascular disease: effect of exercise training Integrative Medicine Research coronary artery disease dysfunctional HDL exercise training high-density lipoprotein cholesterol (HDL-C) |
| title | High-density lipoprotein cholesterol (HDL-C) in cardiovascular disease: effect of exercise training |
| title_full | High-density lipoprotein cholesterol (HDL-C) in cardiovascular disease: effect of exercise training |
| title_fullStr | High-density lipoprotein cholesterol (HDL-C) in cardiovascular disease: effect of exercise training |
| title_full_unstemmed | High-density lipoprotein cholesterol (HDL-C) in cardiovascular disease: effect of exercise training |
| title_short | High-density lipoprotein cholesterol (HDL-C) in cardiovascular disease: effect of exercise training |
| title_sort | high density lipoprotein cholesterol hdl c in cardiovascular disease effect of exercise training |
| topic | coronary artery disease dysfunctional HDL exercise training high-density lipoprotein cholesterol (HDL-C) |
| url | http://www.sciencedirect.com/science/article/pii/S2213422016300737 |
| work_keys_str_mv | AT nayoungahn highdensitylipoproteincholesterolhdlcincardiovasculardiseaseeffectofexercisetraining AT kijinkim highdensitylipoproteincholesterolhdlcincardiovasculardiseaseeffectofexercisetraining |