Neural Stimulation of Brain Organoids with Dynamic Patterns: A Sentiomics Approach Directed to Regenerative Neuromedicine
The new science called <i>Sentiomics</i> aims to identify the dynamic patterns that endow living systems with the capacity to feel and become conscious. One of the most promising fields of investigation in <i>Sentiomics</i> is the development and ‘education’ of human brain or...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
|
Series: | NeuroSci |
Subjects: | |
Online Access: | https://www.mdpi.com/2673-4087/4/1/4 |
_version_ | 1797609743554969600 |
---|---|
author | Alfredo Pereira José Wagner Garcia Alysson Muotri |
author_facet | Alfredo Pereira José Wagner Garcia Alysson Muotri |
author_sort | Alfredo Pereira |
collection | DOAJ |
description | The new science called <i>Sentiomics</i> aims to identify the dynamic patterns that endow living systems with the capacity to feel and become conscious. One of the most promising fields of investigation in <i>Sentiomics</i> is the development and ‘education’ of human brain organoids to become sentient and useful for the promotion of human health in the (also new) field of Regenerative Neuromedicine. Here, we discuss the type of informational-rich input necessary to make a brain organoid sentient in experimental settings. Combining this research with the ecological preoccupation of preserving ways of sentience in the Amazon Rainforest, we also envisage the development of a new generation of biosensors to capture dynamic patterns from the forest, and use them in the ‘education’ of brain organoids to afford them a ‘mental health’ quality that is likely to be important in future advances in ‘post-humanist’ procedures in regenerative medicine. This study is closely related to the psychophysical approach to human mental health therapy, in which we have proposed the use of dynamic patterns in electric and magnetic brain stimulation protocols, addressing electrochemical waves in neuro-astroglial networks. |
first_indexed | 2024-03-11T06:05:33Z |
format | Article |
id | doaj.art-d65f6c965ca14b418111d3d726baa81c |
institution | Directory Open Access Journal |
issn | 2673-4087 |
language | English |
last_indexed | 2024-03-11T06:05:33Z |
publishDate | 2023-01-01 |
publisher | MDPI AG |
record_format | Article |
series | NeuroSci |
spelling | doaj.art-d65f6c965ca14b418111d3d726baa81c2023-11-17T13:02:46ZengMDPI AGNeuroSci2673-40872023-01-0141314210.3390/neurosci4010004Neural Stimulation of Brain Organoids with Dynamic Patterns: A Sentiomics Approach Directed to Regenerative NeuromedicineAlfredo Pereira0José Wagner Garcia1Alysson Muotri2Philosophy Graduate Program, UNESP/Marilia Campus, São Paulo State University, Botucatu 18618-689, BrazilArchitecture and Urbanism, USP and PUC, São Paulo, BrazilStem Cell Program, Department of Pediatrics & Cellular Molecular Medicine/UCSD, Institute for Genomic Medicine, San Diego, CA, USAThe new science called <i>Sentiomics</i> aims to identify the dynamic patterns that endow living systems with the capacity to feel and become conscious. One of the most promising fields of investigation in <i>Sentiomics</i> is the development and ‘education’ of human brain organoids to become sentient and useful for the promotion of human health in the (also new) field of Regenerative Neuromedicine. Here, we discuss the type of informational-rich input necessary to make a brain organoid sentient in experimental settings. Combining this research with the ecological preoccupation of preserving ways of sentience in the Amazon Rainforest, we also envisage the development of a new generation of biosensors to capture dynamic patterns from the forest, and use them in the ‘education’ of brain organoids to afford them a ‘mental health’ quality that is likely to be important in future advances in ‘post-humanist’ procedures in regenerative medicine. This study is closely related to the psychophysical approach to human mental health therapy, in which we have proposed the use of dynamic patterns in electric and magnetic brain stimulation protocols, addressing electrochemical waves in neuro-astroglial networks.https://www.mdpi.com/2673-4087/4/1/4brain organoidssentiomicsregenerative neuromedicinedynamic patternsAmazon Rainforest |
spellingShingle | Alfredo Pereira José Wagner Garcia Alysson Muotri Neural Stimulation of Brain Organoids with Dynamic Patterns: A Sentiomics Approach Directed to Regenerative Neuromedicine NeuroSci brain organoids sentiomics regenerative neuromedicine dynamic patterns Amazon Rainforest |
title | Neural Stimulation of Brain Organoids with Dynamic Patterns: A Sentiomics Approach Directed to Regenerative Neuromedicine |
title_full | Neural Stimulation of Brain Organoids with Dynamic Patterns: A Sentiomics Approach Directed to Regenerative Neuromedicine |
title_fullStr | Neural Stimulation of Brain Organoids with Dynamic Patterns: A Sentiomics Approach Directed to Regenerative Neuromedicine |
title_full_unstemmed | Neural Stimulation of Brain Organoids with Dynamic Patterns: A Sentiomics Approach Directed to Regenerative Neuromedicine |
title_short | Neural Stimulation of Brain Organoids with Dynamic Patterns: A Sentiomics Approach Directed to Regenerative Neuromedicine |
title_sort | neural stimulation of brain organoids with dynamic patterns a sentiomics approach directed to regenerative neuromedicine |
topic | brain organoids sentiomics regenerative neuromedicine dynamic patterns Amazon Rainforest |
url | https://www.mdpi.com/2673-4087/4/1/4 |
work_keys_str_mv | AT alfredopereira neuralstimulationofbrainorganoidswithdynamicpatternsasentiomicsapproachdirectedtoregenerativeneuromedicine AT josewagnergarcia neuralstimulationofbrainorganoidswithdynamicpatternsasentiomicsapproachdirectedtoregenerativeneuromedicine AT alyssonmuotri neuralstimulationofbrainorganoidswithdynamicpatternsasentiomicsapproachdirectedtoregenerativeneuromedicine |