Usability of dual HIV/syphilis self-testing among men who have sex with men in China: study protocol for a three-arm randomised controlled trial
Introduction HIV self-testing (HIVST) provides a key measure for the early detection of HIV infection in men who have sex with men (MSM). However, dual HIV/syphilis self-testing in the MSM population has not been studied. We describe a randomised controlled trial to evaluate the effect of dual HIV/s...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2022-10-01
|
| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/10/e059034.full |
| _version_ | 1811337295759933440 |
|---|---|
| author | Min Wang Yun Zhang Chuanyi Ning Hong Zhang Jieling Mo Sumin Tan Haimei Huang Jiawen Zhu Weiyi Tian Jinli Mo Ping Cen |
| author_facet | Min Wang Yun Zhang Chuanyi Ning Hong Zhang Jieling Mo Sumin Tan Haimei Huang Jiawen Zhu Weiyi Tian Jinli Mo Ping Cen |
| author_sort | Min Wang |
| collection | DOAJ |
| description | Introduction HIV self-testing (HIVST) provides a key measure for the early detection of HIV infection in men who have sex with men (MSM). However, dual HIV/syphilis self-testing in the MSM population has not been studied. We describe a randomised controlled trial to evaluate the effect of dual HIV/syphilis self-testing on the testing frequency among MSM in China.Methods and analysis This randomised controlled trial will be implemented in Guangxi, China. 330 MSM, including 255 frequent testers and 75 less frequent testers, will be recruited and randomly assigned in a 1:1:1 ratio into one of three arms: a site-based testing arm, a single HIVST arm and a dual HIV/syphilis self-testing arm. Participants in the single HIVST arm and dual HIV/syphilis self-testing arm will receive two free finger-prick-based HIVST or HIV/syphilis self-testing kits at enrolment. The data will be collected at five separate times: baseline, 3 months, 6 months, 9 months and 12 months. The primary outcome is the mean frequency of HIV testing used by MSM after intervention comparing each group during the study period. The secondary outcome includes changes in sex behaviours (eg, number of male sex partners and the proportion of consistent condom use) and the mean number of HIV tests used by the social network members over the study period.Ethics and dissemination The study protocol was reviewed and approved by the Medical Ethics Committee of Guangxi Medical University, China (20210173). The study results will be disseminated through conferences and academic journals.Trial registration number ChiCTR2100050898. |
| first_indexed | 2024-04-13T17:52:45Z |
| format | Article |
| id | doaj.art-d6609a9502904c2cbf8b71ea565fab19 |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-04-13T17:52:45Z |
| publishDate | 2022-10-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-d6609a9502904c2cbf8b71ea565fab192022-12-22T02:36:38ZengBMJ Publishing GroupBMJ Open2044-60552022-10-01121010.1136/bmjopen-2021-059034Usability of dual HIV/syphilis self-testing among men who have sex with men in China: study protocol for a three-arm randomised controlled trialMin Wang0Yun Zhang1Chuanyi Ning2Hong Zhang3Jieling Mo4Sumin Tan5Haimei Huang6Jiawen Zhu7Weiyi Tian8Jinli Mo9Ping Cen10Nursing College, Guangxi Medical University, Nanning, Guangxi, ChinaNursing College, Guangxi Medical University, Nanning, Guangxi, ChinaNursing College, Guangxi Medical University, Nanning, Guangxi, ChinaLife Sciences Institute, Guangxi Medical University, Nanning, Guangxi, ChinaNursing College, Guangxi Medical University, Nanning, Guangxi, ChinaNursing College, Guangxi Medical University, Nanning, Guangxi, ChinaNursing College, Guangxi Medical University, Nanning, Guangxi, ChinaThe Second Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, ChinaNursing College, Guangxi Medical University, Nanning, Guangxi, ChinaThe Second Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, ChinaAIDS/STD Control and Prevention, Nanning Municipal Center for Disease Prevention and Control, Nanning, Guangxi, ChinaIntroduction HIV self-testing (HIVST) provides a key measure for the early detection of HIV infection in men who have sex with men (MSM). However, dual HIV/syphilis self-testing in the MSM population has not been studied. We describe a randomised controlled trial to evaluate the effect of dual HIV/syphilis self-testing on the testing frequency among MSM in China.Methods and analysis This randomised controlled trial will be implemented in Guangxi, China. 330 MSM, including 255 frequent testers and 75 less frequent testers, will be recruited and randomly assigned in a 1:1:1 ratio into one of three arms: a site-based testing arm, a single HIVST arm and a dual HIV/syphilis self-testing arm. Participants in the single HIVST arm and dual HIV/syphilis self-testing arm will receive two free finger-prick-based HIVST or HIV/syphilis self-testing kits at enrolment. The data will be collected at five separate times: baseline, 3 months, 6 months, 9 months and 12 months. The primary outcome is the mean frequency of HIV testing used by MSM after intervention comparing each group during the study period. The secondary outcome includes changes in sex behaviours (eg, number of male sex partners and the proportion of consistent condom use) and the mean number of HIV tests used by the social network members over the study period.Ethics and dissemination The study protocol was reviewed and approved by the Medical Ethics Committee of Guangxi Medical University, China (20210173). The study results will be disseminated through conferences and academic journals.Trial registration number ChiCTR2100050898.https://bmjopen.bmj.com/content/12/10/e059034.full |
| spellingShingle | Min Wang Yun Zhang Chuanyi Ning Hong Zhang Jieling Mo Sumin Tan Haimei Huang Jiawen Zhu Weiyi Tian Jinli Mo Ping Cen Usability of dual HIV/syphilis self-testing among men who have sex with men in China: study protocol for a three-arm randomised controlled trial BMJ Open |
| title | Usability of dual HIV/syphilis self-testing among men who have sex with men in China: study protocol for a three-arm randomised controlled trial |
| title_full | Usability of dual HIV/syphilis self-testing among men who have sex with men in China: study protocol for a three-arm randomised controlled trial |
| title_fullStr | Usability of dual HIV/syphilis self-testing among men who have sex with men in China: study protocol for a three-arm randomised controlled trial |
| title_full_unstemmed | Usability of dual HIV/syphilis self-testing among men who have sex with men in China: study protocol for a three-arm randomised controlled trial |
| title_short | Usability of dual HIV/syphilis self-testing among men who have sex with men in China: study protocol for a three-arm randomised controlled trial |
| title_sort | usability of dual hiv syphilis self testing among men who have sex with men in china study protocol for a three arm randomised controlled trial |
| url | https://bmjopen.bmj.com/content/12/10/e059034.full |
| work_keys_str_mv | AT minwang usabilityofdualhivsyphilisselftestingamongmenwhohavesexwithmeninchinastudyprotocolforathreearmrandomisedcontrolledtrial AT yunzhang usabilityofdualhivsyphilisselftestingamongmenwhohavesexwithmeninchinastudyprotocolforathreearmrandomisedcontrolledtrial AT chuanyining usabilityofdualhivsyphilisselftestingamongmenwhohavesexwithmeninchinastudyprotocolforathreearmrandomisedcontrolledtrial AT hongzhang usabilityofdualhivsyphilisselftestingamongmenwhohavesexwithmeninchinastudyprotocolforathreearmrandomisedcontrolledtrial AT jielingmo usabilityofdualhivsyphilisselftestingamongmenwhohavesexwithmeninchinastudyprotocolforathreearmrandomisedcontrolledtrial AT sumintan usabilityofdualhivsyphilisselftestingamongmenwhohavesexwithmeninchinastudyprotocolforathreearmrandomisedcontrolledtrial AT haimeihuang usabilityofdualhivsyphilisselftestingamongmenwhohavesexwithmeninchinastudyprotocolforathreearmrandomisedcontrolledtrial AT jiawenzhu usabilityofdualhivsyphilisselftestingamongmenwhohavesexwithmeninchinastudyprotocolforathreearmrandomisedcontrolledtrial AT weiyitian usabilityofdualhivsyphilisselftestingamongmenwhohavesexwithmeninchinastudyprotocolforathreearmrandomisedcontrolledtrial AT jinlimo usabilityofdualhivsyphilisselftestingamongmenwhohavesexwithmeninchinastudyprotocolforathreearmrandomisedcontrolledtrial AT pingcen usabilityofdualhivsyphilisselftestingamongmenwhohavesexwithmeninchinastudyprotocolforathreearmrandomisedcontrolledtrial |