Vincristine polyneuropathy in children with acute lymphoblastic leukemia: the association with the hereditary rs924607 polymorphism in the <i>CEP72</i> gene

Vincristine polyneuropathy in children with acute lymphoblastic leukemia: the association with the hereditary rs924607 polymorphism in the <i>CEP72</i> gene

Background: Vincristine polyneuropathy is a major neurotoxic complication of treatment for acute lymphoblastic leukemia in children. A close relationship between genetic variants in candidate genes associated with the vincristine neurotoxicity in various ethnic groups has been proposed. Therefore, i...

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Bibliographic Details
Main Authors: Oksana V. Koryakina, Olga P. Kovtun, Grigory A. Tsaur, Elena V. Tsyganko, Larisa G. Fechina, Vladimir V. Bazarnyi
Format: Article
Language:Russian
Published: MONIKI 2023-08-01
Series:Alʹmanah Kliničeskoj Mediciny
Subjects:
vincristine
neurotoxicity
acute leukemia
polyneuropathy
genetic variant
cep72
Online Access:https://almclinmed.ru/jour/article/viewFile/11753/1571

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