Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weeds
Strigolactone agonists could potentially help control noxious weeds by promoting suicidal germination. Here the authors describe a series of small molecule agonists that stimulate germination via the Striga ShHTL7 receptor and show that stereochemistry and hydrolysis-independent signalling mediate p...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31710-9 |
| _version_ | 1811323541277114368 |
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| author | Dawei Wang Zhili Pang Haiyang Yu Benjamin Thiombiano Aimee Walmsley Shuyi Yu Yingying Zhang Tao Wei Lu Liang Jing Wang Xin Wen Harro J. Bouwmeester Ruifeng Yao Zhen Xi |
| author_facet | Dawei Wang Zhili Pang Haiyang Yu Benjamin Thiombiano Aimee Walmsley Shuyi Yu Yingying Zhang Tao Wei Lu Liang Jing Wang Xin Wen Harro J. Bouwmeester Ruifeng Yao Zhen Xi |
| author_sort | Dawei Wang |
| collection | DOAJ |
| description | Strigolactone agonists could potentially help control noxious weeds by promoting suicidal germination. Here the authors describe a series of small molecule agonists that stimulate germination via the Striga ShHTL7 receptor and show that stereochemistry and hydrolysis-independent signalling mediate potency. |
| first_indexed | 2024-04-13T13:57:00Z |
| format | Article |
| id | doaj.art-d662ae6b85d9485ea659daca3ceb74ff |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T13:57:00Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-d662ae6b85d9485ea659daca3ceb74ff2022-12-22T02:44:11ZengNature PortfolioNature Communications2041-17232022-07-0113111210.1038/s41467-022-31710-9Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weedsDawei Wang0Zhili Pang1Haiyang Yu2Benjamin Thiombiano3Aimee Walmsley4Shuyi Yu5Yingying Zhang6Tao Wei7Lu Liang8Jing Wang9Xin Wen10Harro J. Bouwmeester11Ruifeng Yao12Zhen Xi13State Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai UniversityState Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai UniversityState Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan Provincial Key Laboratory of Plant Functional Genomics and Developmental Regulation, College of Biology, Hunan UniversitySwammerdam Institute for Life Sciences (SILS), University of AmsterdamSwammerdam Institute for Life Sciences (SILS), University of AmsterdamState Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai UniversityState Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai UniversityState Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai UniversityState Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai UniversityState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking UniversityState Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai UniversitySwammerdam Institute for Life Sciences (SILS), University of AmsterdamState Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan Provincial Key Laboratory of Plant Functional Genomics and Developmental Regulation, College of Biology, Hunan UniversityState Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai UniversityStrigolactone agonists could potentially help control noxious weeds by promoting suicidal germination. Here the authors describe a series of small molecule agonists that stimulate germination via the Striga ShHTL7 receptor and show that stereochemistry and hydrolysis-independent signalling mediate potency.https://doi.org/10.1038/s41467-022-31710-9 |
| spellingShingle | Dawei Wang Zhili Pang Haiyang Yu Benjamin Thiombiano Aimee Walmsley Shuyi Yu Yingying Zhang Tao Wei Lu Liang Jing Wang Xin Wen Harro J. Bouwmeester Ruifeng Yao Zhen Xi Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weeds Nature Communications |
| title | Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weeds |
| title_full | Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weeds |
| title_fullStr | Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weeds |
| title_full_unstemmed | Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weeds |
| title_short | Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weeds |
| title_sort | probing strigolactone perception mechanisms with rationally designed small molecule agonists stimulating germination of root parasitic weeds |
| url | https://doi.org/10.1038/s41467-022-31710-9 |
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