Implementation of the hemoprophylactic protocol in orthopedic surgery

Introduction: Antibiotic prophylaxis is defined as the use of antimicrobials in the absence of symptoms of infection, with the aim of preventing or reducing the incidence of infection after surgery. We analyzed the incidence of surgical wound infection in patients in whom a protection of hemoprophyl...

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Main Authors: Elvedin Osmanovic, Mensura Aščerić, Esed Omerkic
Format: Article
Language:English
Published: University of Sarajevo 2011-12-01
Series:Journal of Health Sciences
Subjects:
Online Access:https://www.jhsci.ba/ojs/index.php/jhsci/article/view/40
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author Elvedin Osmanovic
Mensura Aščerić
Esed Omerkic
author_facet Elvedin Osmanovic
Mensura Aščerić
Esed Omerkic
author_sort Elvedin Osmanovic
collection DOAJ
description Introduction: Antibiotic prophylaxis is defined as the use of antimicrobials in the absence of symptoms of infection, with the aim of preventing or reducing the incidence of infection after surgery. We analyzed the incidence of surgical wound infection in patients in whom a protection of hemoprophylaxis conducted using cefazolin and gentamicin, and determine the frequency of surgical wound infection in patients in whom there was a deviation in the implementation of hemoprophylaxis protection. Methods: This retrospective-prospective study included 100 patients surgically treated at the The Department of Orthopedics and Traumatology, University Clinical Center in Tuzla from December 2007 to February 2010, which examined the incidence of surgical wound infection after surgical treatment of fractures or degenerative changes in the hip, thigh and lower leg fractures. Results: In the first group, in patients who were treated with cefazolin were detected in 2 cases (5.7%) while the length of hemoprophylaxis was 7 days, patients who were treated with cefazolin and gentamicin were detected in 1 case (2.8%) and duration hemoprophylaxis was 7 days. In another control group tah was found 9 cases of wound infection (30%), and hemoprophylaxis duration was 10 days. Conclusion: The combination of cefazolin and gentamycin for a period of 5 days significantly reduces the incidence of infection and significantly shortened the time of antibiotics in group that is respected application protocol in accordance with international recommendation.
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spelling doaj.art-d663eeb71d7b4b07bfb3c0fdf0a48aea2022-12-21T20:28:57ZengUniversity of SarajevoJournal of Health Sciences2232-75761986-80492011-12-011310.17532/jhsci.2011.13340Implementation of the hemoprophylactic protocol in orthopedic surgeryElvedin Osmanovic0Mensura Aščerić1Esed Omerkic2Emergency Department, Public Health Institution Health Centre Zivinice, Bosnia and HerzegovinaDepartment of Clinical Pharmacology and Toxicology, Medical Faculty Tuzla, University of Tuzla, Univerzitetska 1, 75000 Tuzla, Bosnia and HerzegovinaEmergency Department, Public Health Institution Health Centre Zivinice, Bosnia and HerzegovinaIntroduction: Antibiotic prophylaxis is defined as the use of antimicrobials in the absence of symptoms of infection, with the aim of preventing or reducing the incidence of infection after surgery. We analyzed the incidence of surgical wound infection in patients in whom a protection of hemoprophylaxis conducted using cefazolin and gentamicin, and determine the frequency of surgical wound infection in patients in whom there was a deviation in the implementation of hemoprophylaxis protection. Methods: This retrospective-prospective study included 100 patients surgically treated at the The Department of Orthopedics and Traumatology, University Clinical Center in Tuzla from December 2007 to February 2010, which examined the incidence of surgical wound infection after surgical treatment of fractures or degenerative changes in the hip, thigh and lower leg fractures. Results: In the first group, in patients who were treated with cefazolin were detected in 2 cases (5.7%) while the length of hemoprophylaxis was 7 days, patients who were treated with cefazolin and gentamicin were detected in 1 case (2.8%) and duration hemoprophylaxis was 7 days. In another control group tah was found 9 cases of wound infection (30%), and hemoprophylaxis duration was 10 days. Conclusion: The combination of cefazolin and gentamycin for a period of 5 days significantly reduces the incidence of infection and significantly shortened the time of antibiotics in group that is respected application protocol in accordance with international recommendation.https://www.jhsci.ba/ojs/index.php/jhsci/article/view/40infectionsorthopaedicprophylaxisantibioticcefazolingentamycin
spellingShingle Elvedin Osmanovic
Mensura Aščerić
Esed Omerkic
Implementation of the hemoprophylactic protocol in orthopedic surgery
Journal of Health Sciences
infections
orthopaedic
prophylaxis
antibiotic
cefazolin
gentamycin
title Implementation of the hemoprophylactic protocol in orthopedic surgery
title_full Implementation of the hemoprophylactic protocol in orthopedic surgery
title_fullStr Implementation of the hemoprophylactic protocol in orthopedic surgery
title_full_unstemmed Implementation of the hemoprophylactic protocol in orthopedic surgery
title_short Implementation of the hemoprophylactic protocol in orthopedic surgery
title_sort implementation of the hemoprophylactic protocol in orthopedic surgery
topic infections
orthopaedic
prophylaxis
antibiotic
cefazolin
gentamycin
url https://www.jhsci.ba/ojs/index.php/jhsci/article/view/40
work_keys_str_mv AT elvedinosmanovic implementationofthehemoprophylacticprotocolinorthopedicsurgery
AT mensuraasceric implementationofthehemoprophylacticprotocolinorthopedicsurgery
AT esedomerkic implementationofthehemoprophylacticprotocolinorthopedicsurgery