Induction of Low-Level Hydrogen Peroxide Generation by Unbleached Cotton Nonwovens as Potential Wound Dressing Materials
Greige cotton is an intact plant fiber. The cuticle and primary cell wall near the outer surface of the cotton fiber contains pectin, peroxidases, superoxide dismutase (SOD), and trace metals, which are associated with hydrogen peroxide (H2O2) generation during cotton fiber development. Traditionall...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-03-01
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| Series: | Journal of Functional Biomaterials |
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| Online Access: | http://www.mdpi.com/2079-4983/8/1/9 |
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| author | J. Vincent Edwards Nicolette T. Prevost Sunghyun Nam Doug Hinchliffe Brian Condon Dorne Yager |
| author_facet | J. Vincent Edwards Nicolette T. Prevost Sunghyun Nam Doug Hinchliffe Brian Condon Dorne Yager |
| author_sort | J. Vincent Edwards |
| collection | DOAJ |
| description | Greige cotton is an intact plant fiber. The cuticle and primary cell wall near the outer surface of the cotton fiber contains pectin, peroxidases, superoxide dismutase (SOD), and trace metals, which are associated with hydrogen peroxide (H2O2) generation during cotton fiber development. Traditionally, the processing of cotton into gauze involves scouring and bleaching processes that remove the components in the cuticle and primary cell wall. The use of unbleached, greige cotton fibers in dressings, has been relatively unexplored. We have recently determined that greige cotton can generate low levels of H2O2 (5–50 micromolar). Because this may provide advantages for the use of greige cotton-based wound dressings, we have begun to examine this in more detail. Both brown and white cotton varieties were examined in this study. Brown cotton was found to have a relatively higher hydrogen peroxide generation and demonstrated different capacities for H2O2 generation, varying from 1 to 35 micromolar. The H2O2 generation capacities of white and brown nonwoven greige cottons were also examined at different process stages with varying chronology and source parameters, from field to nonwoven fiber. The primary cell wall of nonwoven brown cotton appeared very intact, as observed by transmission electron microscopy, and possessed higher pectin levels. The levels of pectin, SOD, and polyphenolics, correlated with H2O2 generation. |
| first_indexed | 2024-04-13T08:25:04Z |
| format | Article |
| id | doaj.art-d6647bfac3de42588947f75053850c1a |
| institution | Directory Open Access Journal |
| issn | 2079-4983 |
| language | English |
| last_indexed | 2024-04-13T08:25:04Z |
| publishDate | 2017-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Biomaterials |
| spelling | doaj.art-d6647bfac3de42588947f75053850c1a2022-12-22T02:54:32ZengMDPI AGJournal of Functional Biomaterials2079-49832017-03-0181910.3390/jfb8010009jfb8010009Induction of Low-Level Hydrogen Peroxide Generation by Unbleached Cotton Nonwovens as Potential Wound Dressing MaterialsJ. Vincent Edwards0Nicolette T. Prevost1Sunghyun Nam2Doug Hinchliffe3Brian Condon4Dorne Yager5United States Department of Agriculture, Southern Regional Research Center, New Orleans, LA 70124, USAUnited States Department of Agriculture, Southern Regional Research Center, New Orleans, LA 70124, USAUnited States Department of Agriculture, Southern Regional Research Center, New Orleans, LA 70124, USAUnited States Department of Agriculture, Southern Regional Research Center, New Orleans, LA 70124, USAUnited States Department of Agriculture, Southern Regional Research Center, New Orleans, LA 70124, USAPlastic and Reconstructive Surgery, Virginia Commonwealth University, Richmond, VA 23111, USAGreige cotton is an intact plant fiber. The cuticle and primary cell wall near the outer surface of the cotton fiber contains pectin, peroxidases, superoxide dismutase (SOD), and trace metals, which are associated with hydrogen peroxide (H2O2) generation during cotton fiber development. Traditionally, the processing of cotton into gauze involves scouring and bleaching processes that remove the components in the cuticle and primary cell wall. The use of unbleached, greige cotton fibers in dressings, has been relatively unexplored. We have recently determined that greige cotton can generate low levels of H2O2 (5–50 micromolar). Because this may provide advantages for the use of greige cotton-based wound dressings, we have begun to examine this in more detail. Both brown and white cotton varieties were examined in this study. Brown cotton was found to have a relatively higher hydrogen peroxide generation and demonstrated different capacities for H2O2 generation, varying from 1 to 35 micromolar. The H2O2 generation capacities of white and brown nonwoven greige cottons were also examined at different process stages with varying chronology and source parameters, from field to nonwoven fiber. The primary cell wall of nonwoven brown cotton appeared very intact, as observed by transmission electron microscopy, and possessed higher pectin levels. The levels of pectin, SOD, and polyphenolics, correlated with H2O2 generation.http://www.mdpi.com/2079-4983/8/1/9hydrogen peroxidechronic woundscottonwound dressingswound healing |
| spellingShingle | J. Vincent Edwards Nicolette T. Prevost Sunghyun Nam Doug Hinchliffe Brian Condon Dorne Yager Induction of Low-Level Hydrogen Peroxide Generation by Unbleached Cotton Nonwovens as Potential Wound Dressing Materials Journal of Functional Biomaterials hydrogen peroxide chronic wounds cotton wound dressings wound healing |
| title | Induction of Low-Level Hydrogen Peroxide Generation by Unbleached Cotton Nonwovens as Potential Wound Dressing Materials |
| title_full | Induction of Low-Level Hydrogen Peroxide Generation by Unbleached Cotton Nonwovens as Potential Wound Dressing Materials |
| title_fullStr | Induction of Low-Level Hydrogen Peroxide Generation by Unbleached Cotton Nonwovens as Potential Wound Dressing Materials |
| title_full_unstemmed | Induction of Low-Level Hydrogen Peroxide Generation by Unbleached Cotton Nonwovens as Potential Wound Dressing Materials |
| title_short | Induction of Low-Level Hydrogen Peroxide Generation by Unbleached Cotton Nonwovens as Potential Wound Dressing Materials |
| title_sort | induction of low level hydrogen peroxide generation by unbleached cotton nonwovens as potential wound dressing materials |
| topic | hydrogen peroxide chronic wounds cotton wound dressings wound healing |
| url | http://www.mdpi.com/2079-4983/8/1/9 |
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