Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives
We present 1-pentafluorophenyl-1H-pyrrole and some of its electrophilic substitution reactions: formylation and acetylations. The 2-substituted products formed in these reactions are selectively and in high yield converted into 3-substituted products by treatment with trifluoromethanesulfonic acid....
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| Format: | Article |
| Language: | English |
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MDPI AG
2003-07-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/8/7/536/ |
| _version_ | 1811237771029774336 |
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| author | Daniel Végh KatarÃÂna HrnÄÂariková |
| author_facet | Daniel Végh KatarÃÂna HrnÄÂariková |
| author_sort | Daniel Végh |
| collection | DOAJ |
| description | We present 1-pentafluorophenyl-1H-pyrrole and some of its electrophilic substitution reactions: formylation and acetylations. The 2-substituted products formed in these reactions are selectively and in high yield converted into 3-substituted products by treatment with trifluoromethanesulfonic acid. A general synthesis of 3-acylpyrroles was developed by the trifluoromethanesulfonic acid-mediated rearrangement of the corresponding 2-acylpyrroles. |
| first_indexed | 2024-04-12T12:30:11Z |
| format | Article |
| id | doaj.art-d66ac33286f64826bc3c96d11d1c2faa |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-12T12:30:11Z |
| publishDate | 2003-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-d66ac33286f64826bc3c96d11d1c2faa2022-12-22T03:33:04ZengMDPI AGMolecules1420-30492003-07-018753654010.3390/80700536Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole DerivativesDaniel VéghKatarÃÂna HrnÄÂarikováWe present 1-pentafluorophenyl-1H-pyrrole and some of its electrophilic substitution reactions: formylation and acetylations. The 2-substituted products formed in these reactions are selectively and in high yield converted into 3-substituted products by treatment with trifluoromethanesulfonic acid. A general synthesis of 3-acylpyrroles was developed by the trifluoromethanesulfonic acid-mediated rearrangement of the corresponding 2-acylpyrroles.http://www.mdpi.com/1420-3049/8/7/536/Conducting materialssupramolecular synthonspyrroles |
| spellingShingle | Daniel Végh KatarÃÂna HrnÄÂariková Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives Molecules Conducting materials supramolecular synthons pyrroles |
| title | Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives |
| title_full | Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives |
| title_fullStr | Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives |
| title_full_unstemmed | Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives |
| title_short | Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives |
| title_sort | synthesis and reactivity of new 1 pentafluorophenyl 1hpyrrole derivatives |
| topic | Conducting materials supramolecular synthons pyrroles |
| url | http://www.mdpi.com/1420-3049/8/7/536/ |
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