Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress

Neoadjuvant chemotherapy (NAC) for breast cancer is widely used in the clinical setting to improve the chance of surgery, breast conservation and quality of life for patients with advanced breast cancer. A more accurate efficacy evaluation system is important for the decision of surgery timing and c...

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Main Authors: Yushi Chen, Yu Qi, Kuansong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1169010/full
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author Yushi Chen
Yushi Chen
Yu Qi
Yu Qi
Kuansong Wang
Kuansong Wang
author_facet Yushi Chen
Yushi Chen
Yu Qi
Yu Qi
Kuansong Wang
Kuansong Wang
author_sort Yushi Chen
collection DOAJ
description Neoadjuvant chemotherapy (NAC) for breast cancer is widely used in the clinical setting to improve the chance of surgery, breast conservation and quality of life for patients with advanced breast cancer. A more accurate efficacy evaluation system is important for the decision of surgery timing and chemotherapy regimen implementation. However, current methods, encompassing imaging techniques such as ultrasound and MRI, along with non-imaging approaches like pathological evaluations, often fall short in accurately depicting the therapeutic effects of NAC. Imaging techniques are subjective and only reflect macroscopic morphological changes, while pathological evaluation is the gold standard for efficacy assessment but has the disadvantage of delayed results. In an effort to identify assessment methods that align more closely with real-world clinical demands, this paper provides an in-depth exploration of the principles and clinical applications of various assessment approaches in the neoadjuvant chemotherapy process.
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spelling doaj.art-d6702297fef54ce199a220be6fd02da92023-10-03T09:47:25ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-10-011310.3389/fonc.2023.11690101169010Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progressYushi Chen0Yushi Chen1Yu Qi2Yu Qi3Kuansong Wang4Kuansong Wang5Department of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaDepartment of Pathology, Basic Medical School, Central South University, Changsha, Hunan, ChinaDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaDepartment of Pathology, Basic Medical School, Central South University, Changsha, Hunan, ChinaDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaDepartment of Pathology, Basic Medical School, Central South University, Changsha, Hunan, ChinaNeoadjuvant chemotherapy (NAC) for breast cancer is widely used in the clinical setting to improve the chance of surgery, breast conservation and quality of life for patients with advanced breast cancer. A more accurate efficacy evaluation system is important for the decision of surgery timing and chemotherapy regimen implementation. However, current methods, encompassing imaging techniques such as ultrasound and MRI, along with non-imaging approaches like pathological evaluations, often fall short in accurately depicting the therapeutic effects of NAC. Imaging techniques are subjective and only reflect macroscopic morphological changes, while pathological evaluation is the gold standard for efficacy assessment but has the disadvantage of delayed results. In an effort to identify assessment methods that align more closely with real-world clinical demands, this paper provides an in-depth exploration of the principles and clinical applications of various assessment approaches in the neoadjuvant chemotherapy process.https://www.frontiersin.org/articles/10.3389/fonc.2023.1169010/fullbreast cancerneoadjuvant chemotherapytreatmentevaluationimaging technique
spellingShingle Yushi Chen
Yushi Chen
Yu Qi
Yu Qi
Kuansong Wang
Kuansong Wang
Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress
Frontiers in Oncology
breast cancer
neoadjuvant chemotherapy
treatment
evaluation
imaging technique
title Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress
title_full Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress
title_fullStr Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress
title_full_unstemmed Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress
title_short Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress
title_sort neoadjuvant chemotherapy for breast cancer an evaluation of its efficacy and research progress
topic breast cancer
neoadjuvant chemotherapy
treatment
evaluation
imaging technique
url https://www.frontiersin.org/articles/10.3389/fonc.2023.1169010/full
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