Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress
Neoadjuvant chemotherapy (NAC) for breast cancer is widely used in the clinical setting to improve the chance of surgery, breast conservation and quality of life for patients with advanced breast cancer. A more accurate efficacy evaluation system is important for the decision of surgery timing and c...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2023-10-01
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Series: | Frontiers in Oncology |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1169010/full |
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author | Yushi Chen Yushi Chen Yu Qi Yu Qi Kuansong Wang Kuansong Wang |
author_facet | Yushi Chen Yushi Chen Yu Qi Yu Qi Kuansong Wang Kuansong Wang |
author_sort | Yushi Chen |
collection | DOAJ |
description | Neoadjuvant chemotherapy (NAC) for breast cancer is widely used in the clinical setting to improve the chance of surgery, breast conservation and quality of life for patients with advanced breast cancer. A more accurate efficacy evaluation system is important for the decision of surgery timing and chemotherapy regimen implementation. However, current methods, encompassing imaging techniques such as ultrasound and MRI, along with non-imaging approaches like pathological evaluations, often fall short in accurately depicting the therapeutic effects of NAC. Imaging techniques are subjective and only reflect macroscopic morphological changes, while pathological evaluation is the gold standard for efficacy assessment but has the disadvantage of delayed results. In an effort to identify assessment methods that align more closely with real-world clinical demands, this paper provides an in-depth exploration of the principles and clinical applications of various assessment approaches in the neoadjuvant chemotherapy process. |
first_indexed | 2024-03-11T20:18:27Z |
format | Article |
id | doaj.art-d6702297fef54ce199a220be6fd02da9 |
institution | Directory Open Access Journal |
issn | 2234-943X |
language | English |
last_indexed | 2024-03-11T20:18:27Z |
publishDate | 2023-10-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Oncology |
spelling | doaj.art-d6702297fef54ce199a220be6fd02da92023-10-03T09:47:25ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-10-011310.3389/fonc.2023.11690101169010Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progressYushi Chen0Yushi Chen1Yu Qi2Yu Qi3Kuansong Wang4Kuansong Wang5Department of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaDepartment of Pathology, Basic Medical School, Central South University, Changsha, Hunan, ChinaDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaDepartment of Pathology, Basic Medical School, Central South University, Changsha, Hunan, ChinaDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaDepartment of Pathology, Basic Medical School, Central South University, Changsha, Hunan, ChinaNeoadjuvant chemotherapy (NAC) for breast cancer is widely used in the clinical setting to improve the chance of surgery, breast conservation and quality of life for patients with advanced breast cancer. A more accurate efficacy evaluation system is important for the decision of surgery timing and chemotherapy regimen implementation. However, current methods, encompassing imaging techniques such as ultrasound and MRI, along with non-imaging approaches like pathological evaluations, often fall short in accurately depicting the therapeutic effects of NAC. Imaging techniques are subjective and only reflect macroscopic morphological changes, while pathological evaluation is the gold standard for efficacy assessment but has the disadvantage of delayed results. In an effort to identify assessment methods that align more closely with real-world clinical demands, this paper provides an in-depth exploration of the principles and clinical applications of various assessment approaches in the neoadjuvant chemotherapy process.https://www.frontiersin.org/articles/10.3389/fonc.2023.1169010/fullbreast cancerneoadjuvant chemotherapytreatmentevaluationimaging technique |
spellingShingle | Yushi Chen Yushi Chen Yu Qi Yu Qi Kuansong Wang Kuansong Wang Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress Frontiers in Oncology breast cancer neoadjuvant chemotherapy treatment evaluation imaging technique |
title | Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress |
title_full | Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress |
title_fullStr | Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress |
title_full_unstemmed | Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress |
title_short | Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress |
title_sort | neoadjuvant chemotherapy for breast cancer an evaluation of its efficacy and research progress |
topic | breast cancer neoadjuvant chemotherapy treatment evaluation imaging technique |
url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1169010/full |
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