The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness
OBJECTIVE: The aim of the study was to determine whether it is possible to differentiate submucosal fibroids before interventional procedures based on mean platelet volume (MPV), in reproductive-age patients presenting with endometrial thickening and abnormal uterine bleeding. STUDY DESIGN: This stu...
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| Format: | Article |
| Language: | English |
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Medical Network
2016-04-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
| Subjects: | |
| Online Access: | http://gorm.com.tr/index.php/GORM/article/view/108 |
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| author | Kerem Doğa Seçkin Mehmet Fatih Karslı Burak Yücel Elif Akkaş Yılmaz Murat Öz Deniz Balsak Hüseyin Kıyak Gökhan Yıldırım |
| author_facet | Kerem Doğa Seçkin Mehmet Fatih Karslı Burak Yücel Elif Akkaş Yılmaz Murat Öz Deniz Balsak Hüseyin Kıyak Gökhan Yıldırım |
| author_sort | Kerem Doğa Seçkin |
| collection | DOAJ |
| description | OBJECTIVE: The aim of the study was to determine whether it is possible to differentiate submucosal fibroids before interventional procedures based on mean platelet volume (MPV), in reproductive-age patients presenting with endometrial thickening and abnormal uterine bleeding.
STUDY DESIGN: This study included 581 reproductive-age women who underwent diagnostic procedures (curettage or operative hysteroscopy) and were subsequently divided into two groups based on clinico-pathological findings. The first group included those with benign endometrial pathology (control group, n=438), and the second group consisted of those with submucosal leiomyomas (n=143). The demographic characteristics and complete blood count (CBC) data of these patients were collected retrospectively, and comparisons were made between groups.
RESULTS: No statistically significant difference was found between the groups according to demographic features and CBC parameters such as hemoglobin levels and white blood count (p>0,05). Platelet counts were significantly higher and MPV values were significantly lower in submucosal leiomyoma patients compared with the control subjects (p<0,05).
CONCLUSIONS: MPV may be a useful predictive marker when differentiating submucosal leiomyoma from other benign causes of abnormal uterine bleeding. The ability to predict the possibility of the presence of submucosal leiomyoma before surgery can assist in determining the most appropriate type of invasive procedure. |
| first_indexed | 2024-04-10T11:40:07Z |
| format | Article |
| id | doaj.art-d67326ef07bb4ade9957d2b26ae38be9 |
| institution | Directory Open Access Journal |
| issn | 1300-4751 |
| language | English |
| last_indexed | 2024-04-10T11:40:07Z |
| publishDate | 2016-04-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj.art-d67326ef07bb4ade9957d2b26ae38be92023-02-15T16:17:36ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512016-04-0122110.21613/GORM.2016.10851The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial ThicknessKerem Doğa Seçkin0Mehmet Fatih Karslı1Burak Yücel2Elif Akkaş Yılmaz3Murat Öz4Deniz Balsak5Hüseyin Kıyak6Gökhan Yıldırım7Department of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital, IstanbulDepartment of Obstetrics and Gynaecology, Sami Ulus Women and Children Health Training and Research Hospital, AnkaraDepartment of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital, IstanbulDepartment of Obstetrics and Gynaecology, Sami Ulus Women and Children Health Training and Research Hospital, AnkaraDepartment of Obstetrics and Gynaecology, Zekai Tahir Burak Womens’ Health and Research Hospital, AnkaraDepartment of Obstetrics and Gynaecology, Halic University, IstanbulDepartment of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital, IstanbulDepartment of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital, IstanbulOBJECTIVE: The aim of the study was to determine whether it is possible to differentiate submucosal fibroids before interventional procedures based on mean platelet volume (MPV), in reproductive-age patients presenting with endometrial thickening and abnormal uterine bleeding. STUDY DESIGN: This study included 581 reproductive-age women who underwent diagnostic procedures (curettage or operative hysteroscopy) and were subsequently divided into two groups based on clinico-pathological findings. The first group included those with benign endometrial pathology (control group, n=438), and the second group consisted of those with submucosal leiomyomas (n=143). The demographic characteristics and complete blood count (CBC) data of these patients were collected retrospectively, and comparisons were made between groups. RESULTS: No statistically significant difference was found between the groups according to demographic features and CBC parameters such as hemoglobin levels and white blood count (p>0,05). Platelet counts were significantly higher and MPV values were significantly lower in submucosal leiomyoma patients compared with the control subjects (p<0,05). CONCLUSIONS: MPV may be a useful predictive marker when differentiating submucosal leiomyoma from other benign causes of abnormal uterine bleeding. The ability to predict the possibility of the presence of submucosal leiomyoma before surgery can assist in determining the most appropriate type of invasive procedure.http://gorm.com.tr/index.php/GORM/article/view/108Mean platelet volume, Endometrial thickness, Submucosal myoma |
| spellingShingle | Kerem Doğa Seçkin Mehmet Fatih Karslı Burak Yücel Elif Akkaş Yılmaz Murat Öz Deniz Balsak Hüseyin Kıyak Gökhan Yıldırım The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness Gynecology Obstetrics & Reproductive Medicine Mean platelet volume, Endometrial thickness, Submucosal myoma |
| title | The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness |
| title_full | The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness |
| title_fullStr | The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness |
| title_full_unstemmed | The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness |
| title_short | The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness |
| title_sort | role of mean platelet volume on distinction of submucosal myomas from other etiologies in increased endometrial thickness |
| topic | Mean platelet volume, Endometrial thickness, Submucosal myoma |
| url | http://gorm.com.tr/index.php/GORM/article/view/108 |
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