Prevalence of and risk factors for diabetic macular edema in a northeastern Chinese population
AIM: To estimate the prevalence of diabetic macular edema (DME) and clinically significant macular edema (CSME), and to assess their risk factors in a population with type 2 diabetic mellitus (T2DM) located in northeast China. METHODS: Patients were included from the Fushun Diabetic Retinopathy Coho...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2022-02-01
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| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/en_publish/2022/2/20220219.pdf |
| _version_ | 1818954638473297920 |
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| author | Zhong Lin Feng-Hua Wang Liang Wen Yu Wang Dong Li Xiao-Xia Ding Yu Dou Gang Zhai Yuan-Bo Liang |
| author_facet | Zhong Lin Feng-Hua Wang Liang Wen Yu Wang Dong Li Xiao-Xia Ding Yu Dou Gang Zhai Yuan-Bo Liang |
| author_sort | Zhong Lin |
| collection | DOAJ |
| description | AIM: To estimate the prevalence of diabetic macular edema (DME) and clinically significant macular edema (CSME), and to assess their risk factors in a population with type 2 diabetic mellitus (T2DM) located in northeast China. METHODS: Patients were included from the Fushun Diabetic Retinopathy Cohort Study (FS-DIRECT), a community-based study conducted in northeast China. The presence of DME and CSME was determined by the Early Treatment Diabetic Retinopathy Study (ETDRS) retinopathy scale of fundus photographs. The age-standardized prevalence of DME and CSME was estimated. The association between DME/CSME and risk factors was analyzed in a multivariate Logistical analysis. RESULTS: A total of 292 (15.4%) and 166 (8.8%) patients were diagnosed as DME and CSME, yielding the age and sex standardized prevalence of 13.5% (95%CI: 11.9%-15.0%), and 7.1% (95%CI: 5.9%-8.3%), respectively. Female patients had a higher prevalence of DME compared to their male counterparts (15.7% vs 10.4%, P=0.03). Multivariable Logistic regression analysis showed that younger age, insulin use, proteinuria, longer duration of diabetes, and higher glycosylated hemoglobin A1c, were associated with the prevalence of DME and CSME. Patients with higher fasting plasma glucose, systolic blood pressure, and blood urea nitrogen were also found to be associated with DME. CONCLUSION: Early fundus screening in diabetic patients is invaluable and given the relatively high prevalence of DME and CSME in this study cohort, those with a high risk of sight threatening maculopathy would invariably benefit from earlier detection. |
| first_indexed | 2024-12-20T10:25:21Z |
| format | Article |
| id | doaj.art-d674b843d5a948e7a3739838e568fb65 |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-12-20T10:25:21Z |
| publishDate | 2022-02-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-d674b843d5a948e7a3739838e568fb652022-12-21T19:43:51ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982022-02-0115232032610.18240/ijo.2022.02.1920220219Prevalence of and risk factors for diabetic macular edema in a northeastern Chinese populationZhong Lin0Feng-Hua Wang1Liang Wen2Yu Wang3Dong Li4Xiao-Xia Ding5Yu Dou6Gang Zhai7Yuan-Bo Liang8Yu Wang. Fushun Eye Hospital, No.1 Hu Po Quan Street, Xin Fu District, Fushun 113006, Liaoning Province, China. fswangyu71@163.comBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical UniversityBeijing Ophthalmology & Visual Science Key Lab, Beijing 100730, ChinaBeijing Ophthalmology & Visual Science Key Lab, Beijing 100730, ChinaBeijing Ophthalmology & Visual Science Key Lab, Beijing 100730, ChinaBeijing Ophthalmology & Visual Science Key Lab, Beijing 100730, ChinaBeijing Ophthalmology & Visual Science Key Lab, Beijing 100730, ChinaBeijing Ophthalmology & Visual Science Key Lab, Beijing 100730, ChinaThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China; National Clinical Research Center for Ocular Diseases, Wenzhou 325027, Zhejiang Province, ChinaAIM: To estimate the prevalence of diabetic macular edema (DME) and clinically significant macular edema (CSME), and to assess their risk factors in a population with type 2 diabetic mellitus (T2DM) located in northeast China. METHODS: Patients were included from the Fushun Diabetic Retinopathy Cohort Study (FS-DIRECT), a community-based study conducted in northeast China. The presence of DME and CSME was determined by the Early Treatment Diabetic Retinopathy Study (ETDRS) retinopathy scale of fundus photographs. The age-standardized prevalence of DME and CSME was estimated. The association between DME/CSME and risk factors was analyzed in a multivariate Logistical analysis. RESULTS: A total of 292 (15.4%) and 166 (8.8%) patients were diagnosed as DME and CSME, yielding the age and sex standardized prevalence of 13.5% (95%CI: 11.9%-15.0%), and 7.1% (95%CI: 5.9%-8.3%), respectively. Female patients had a higher prevalence of DME compared to their male counterparts (15.7% vs 10.4%, P=0.03). Multivariable Logistic regression analysis showed that younger age, insulin use, proteinuria, longer duration of diabetes, and higher glycosylated hemoglobin A1c, were associated with the prevalence of DME and CSME. Patients with higher fasting plasma glucose, systolic blood pressure, and blood urea nitrogen were also found to be associated with DME. CONCLUSION: Early fundus screening in diabetic patients is invaluable and given the relatively high prevalence of DME and CSME in this study cohort, those with a high risk of sight threatening maculopathy would invariably benefit from earlier detection.http://ies.ijo.cn/en_publish/2022/2/20220219.pdfdiabetic macular edemaclinically significant macular edemadiabetic retinopathy |
| spellingShingle | Zhong Lin Feng-Hua Wang Liang Wen Yu Wang Dong Li Xiao-Xia Ding Yu Dou Gang Zhai Yuan-Bo Liang Prevalence of and risk factors for diabetic macular edema in a northeastern Chinese population International Journal of Ophthalmology diabetic macular edema clinically significant macular edema diabetic retinopathy |
| title | Prevalence of and risk factors for diabetic macular edema in a northeastern Chinese population |
| title_full | Prevalence of and risk factors for diabetic macular edema in a northeastern Chinese population |
| title_fullStr | Prevalence of and risk factors for diabetic macular edema in a northeastern Chinese population |
| title_full_unstemmed | Prevalence of and risk factors for diabetic macular edema in a northeastern Chinese population |
| title_short | Prevalence of and risk factors for diabetic macular edema in a northeastern Chinese population |
| title_sort | prevalence of and risk factors for diabetic macular edema in a northeastern chinese population |
| topic | diabetic macular edema clinically significant macular edema diabetic retinopathy |
| url | http://ies.ijo.cn/en_publish/2022/2/20220219.pdf |
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