The structure of the hematopoietic system can explain chronic myeloid leukemia progression

Abstract Almost all cancer types share the hallmarks of cancer and a similar tumor formation: fueled by stochastic mutations in somatic cells. In case of chronic myeloid leukemia (CML), this evolutionary process can be tracked from an asymptomatic long-lasting chronic phase to a final rapidly evolvi...

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Bibliographic Details
Main Authors: Mario Pérez-Jiménez, Imre Derényi, Gergely J. Szöllősi
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32400-2

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