Botulinum toxin in the treatment of paralytic strabismus and essential blepharospasm
As an alternative to conventional medical and surgical modalities that have met little success in the treatment of paralytic strabismus and essential blepharospasm, we explored the use of botulinum toxin as a treatment of choice in these two disorders. We used botulinum toxin in three patients with...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
1993-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=1993;volume=41;issue=3;spage=121;epage=124;aulast=Thomas |
| _version_ | 1817970930189598720 |
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| author | Thomas Ravi Mathai Annie Rajeev B Sen Subir Jacob Pushpa |
| author_facet | Thomas Ravi Mathai Annie Rajeev B Sen Subir Jacob Pushpa |
| author_sort | Thomas Ravi |
| collection | DOAJ |
| description | As an alternative to conventional medical and surgical modalities that have met little success in the treatment of paralytic strabismus and essential blepharospasm, we explored the use of botulinum toxin as a treatment of choice in these two disorders. We used botulinum toxin in three patients with paralytic strabismus and in nine patients with essential blepharospasm. In three patients with paralytic strabismus, the botulinum toxin was injected into the ipsilateral antagonist of the paralysed muscle. The preinjection deviations ranged from 18 to 60 prism diopters. Two of these three patients achieved orthotropia around the thirtieth day and thereafter maintained it. The third patient became orthotropic on the eighteenth day, but deviation recurred and therefore required another injection of toxin. In nine patients with essential blepharospasm, botulinum toxin was injected into the orbicularis oculi muscles. Both objective and subjective improvement occurred in all nine patients within seven days and the effect lasted 12 to 15 weeks. Further injection of the toxin produced extremely beneficial results. However, the only significant complication that we encountered in both groups of strabismus and blepharospasm was ptosis, which was usually partial and temporary. From our experience, we advocate the use of botulinum toxin in the treatment of essential blepharospasm. |
| first_indexed | 2024-04-13T20:40:10Z |
| format | Article |
| id | doaj.art-d676ee3f7e9a4f93901b4181968ec297 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 |
| language | English |
| last_indexed | 2024-04-13T20:40:10Z |
| publishDate | 1993-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-d676ee3f7e9a4f93901b4181968ec2972022-12-22T02:30:54ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381993-01-01413121124Botulinum toxin in the treatment of paralytic strabismus and essential blepharospasmThomas RaviMathai AnnieRajeev BSen SubirJacob PushpaAs an alternative to conventional medical and surgical modalities that have met little success in the treatment of paralytic strabismus and essential blepharospasm, we explored the use of botulinum toxin as a treatment of choice in these two disorders. We used botulinum toxin in three patients with paralytic strabismus and in nine patients with essential blepharospasm. In three patients with paralytic strabismus, the botulinum toxin was injected into the ipsilateral antagonist of the paralysed muscle. The preinjection deviations ranged from 18 to 60 prism diopters. Two of these three patients achieved orthotropia around the thirtieth day and thereafter maintained it. The third patient became orthotropic on the eighteenth day, but deviation recurred and therefore required another injection of toxin. In nine patients with essential blepharospasm, botulinum toxin was injected into the orbicularis oculi muscles. Both objective and subjective improvement occurred in all nine patients within seven days and the effect lasted 12 to 15 weeks. Further injection of the toxin produced extremely beneficial results. However, the only significant complication that we encountered in both groups of strabismus and blepharospasm was ptosis, which was usually partial and temporary. From our experience, we advocate the use of botulinum toxin in the treatment of essential blepharospasm.http://www.ijo.in/article.asp?issn=0301-4738;year=1993;volume=41;issue=3;spage=121;epage=124;aulast=ThomasBotulinum toxin - Paralytic strabismus - Essential blepharospasm - EMG. |
| spellingShingle | Thomas Ravi Mathai Annie Rajeev B Sen Subir Jacob Pushpa Botulinum toxin in the treatment of paralytic strabismus and essential blepharospasm Indian Journal of Ophthalmology Botulinum toxin - Paralytic strabismus - Essential blepharospasm - EMG. |
| title | Botulinum toxin in the treatment of paralytic strabismus and essential blepharospasm |
| title_full | Botulinum toxin in the treatment of paralytic strabismus and essential blepharospasm |
| title_fullStr | Botulinum toxin in the treatment of paralytic strabismus and essential blepharospasm |
| title_full_unstemmed | Botulinum toxin in the treatment of paralytic strabismus and essential blepharospasm |
| title_short | Botulinum toxin in the treatment of paralytic strabismus and essential blepharospasm |
| title_sort | botulinum toxin in the treatment of paralytic strabismus and essential blepharospasm |
| topic | Botulinum toxin - Paralytic strabismus - Essential blepharospasm - EMG. |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=1993;volume=41;issue=3;spage=121;epage=124;aulast=Thomas |
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