Independent Protection and Influence of the Spike-Specific Antibody Response of SARS-CoV-2 Nucleocapsid Protein (N) in Whole-Virion Vaccines

Independent Protection and Influence of the Spike-Specific Antibody Response of SARS-CoV-2 Nucleocapsid Protein (N) in Whole-Virion Vaccines

Of all of the components in SARS-CoV-2 inactivated vaccines, nucleocapsid protein (N) is the most abundant and highly conserved protein. However, the function of N in these vaccines, especially its influence on the targeted spike protein’s response, remains unknown. In this study, the immunization o...

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Bibliographic Details
Main Authors: Huijie Yang, Ying Xie, Shuaiyao Lu, Yufang Sun, Kaiqin Wang, Shuyan Li, Junzhi Wang, Guoyang Liao, Changgui Li
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Vaccines
Subjects:
SARS-CoV-2
nucleocapsid protein
T cell response
S-specific antibody response
whole-virion vaccine
Online Access:https://www.mdpi.com/2076-393X/11/11/1681

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