Evaluation of the toxic potential of aspartame in third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9

Aspartame is commonly used as a sweetener in prepared foods, beverages and in recipes. In the present study the possible toxic effects of aspartame were studied in third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9. The third instar larvae were allowed to feed on the diet hav...

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Bibliographic Details
Main Authors: YASIR HASAN SIDDIQUE, Simmi Anjum, Rahul x, Smita Jyoti
Format: Article
Language:English
Published: Society for the Improvement of Science (SACSIS) 2017-07-01
Series:All Results Journals: Biol
Subjects:
Online Access:http://arjournals.com/index.php/Biol/article/view/151
Description
Summary:Aspartame is commonly used as a sweetener in prepared foods, beverages and in recipes. In the present study the possible toxic effects of aspartame were studied in third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9. The third instar larvae were allowed to feed on the diet having different doses of aspartame. The results obtained in the present study suggest that the exposure of third instar larvae to the diet having 20, 40, 80, 160 and 320 mM of aspartame did not show any significant the toxic effects after 24 hours of the exposure compared to control (p<0.05). The results for pupae formation and emergence of flies also did not show any significant difference compared to control (p<0.05).
ISSN:2172-4784