Tapering of prescribed opioids in patients with long-term non-malignant pain (TOPIO)—efficacy and effects on pain, pain cognitions, and quality of life: a study protocol for a randomized controlled clinical trial with a 12-month follow-up

Tapering of prescribed opioids in patients with long-term non-malignant pain (TOPIO)—efficacy and effects on pain, pain cognitions, and quality of life: a study protocol for a randomized controlled clinical trial with a 12-month follow-up

Abstract Background Opioids are still widely prescribed to long-term pain patients although they are no longer recommended for long-term treatments due to poor evidence for long-term efficacy, risks of serious side effects, and the possibility of inducing opioid hyperalgesia. In a Cochrane study fro...

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Bibliographic Details
Main Authors: Grelz Henrik, Midlöv Patrik, Håkansson Anders, Jakobsson Ulf, Rivano Fischer Marcelo, Ringqvist Åsa
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Trials
Subjects:
Opioid
Long-term pain
Chronic pain
Prescribed
Tapering
Quality of life
Online Access:https://doi.org/10.1186/s13063-021-05449-5

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