Pseudomonas aeruginosa transition from environmental generalist to human pathogen
Opportunistic bacteria Pseudomonas aeruginosa is one of the major concerns as an etiological agent of nosocomial infections in humans. Many virulence factors used to colonize the human body are the same as those used by P. aeruginosa to thrive in the environment such as membrane transport, biofilm...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Universidad San Francisco de Quito USFQ
2021-08-01
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| Series: | ACI Avances en Ciencias e Ingenierías |
| Subjects: | |
| Online Access: | https://revistas.usfq.edu.ec/index.php/avances/article/view/2225 |
| _version_ | 1797280341706145792 |
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| author | Gabriela Vasco Gabriel Trueba |
| author_facet | Gabriela Vasco Gabriel Trueba |
| author_sort | Gabriela Vasco |
| collection | DOAJ |
| description |
Opportunistic bacteria Pseudomonas aeruginosa is one of the major concerns as an etiological agent of nosocomial infections in humans. Many virulence factors used to colonize the human body are the same as those used by P. aeruginosa to thrive in the environment such as membrane transport, biofilm formation, oxidation/reduction reaction, among others. P. aeruginosa origin is mainly from the environment, the adaptation to mammalian tissues may follow a source-sink evolution model; the environment is the source of many lineages, some of them capable of adaptation to the human body. Some lineages may adapt to humans and go through reductive evolution in which some genes are lost. The understanding of this process may be critical to implement better methods to control outbreaks in hospitals.
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| first_indexed | 2024-03-07T16:39:50Z |
| format | Article |
| id | doaj.art-d683ae3fa7474ca986ecf5a8223f4391 |
| institution | Directory Open Access Journal |
| issn | 1390-5384 2528-7788 |
| language | English |
| last_indexed | 2024-03-07T16:39:50Z |
| publishDate | 2021-08-01 |
| publisher | Universidad San Francisco de Quito USFQ |
| record_format | Article |
| series | ACI Avances en Ciencias e Ingenierías |
| spelling | doaj.art-d683ae3fa7474ca986ecf5a8223f43912024-03-03T08:51:22ZengUniversidad San Francisco de Quito USFQACI Avances en Ciencias e Ingenierías1390-53842528-77882021-08-0113110.18272/aci.v13i1.2225Pseudomonas aeruginosa transition from environmental generalist to human pathogenGabriela Vascohttps://orcid.org/0000-0002-8318-2465Gabriel Trueba0https://orcid.org/0000-0003-2617-9021PhD Opportunistic bacteria Pseudomonas aeruginosa is one of the major concerns as an etiological agent of nosocomial infections in humans. Many virulence factors used to colonize the human body are the same as those used by P. aeruginosa to thrive in the environment such as membrane transport, biofilm formation, oxidation/reduction reaction, among others. P. aeruginosa origin is mainly from the environment, the adaptation to mammalian tissues may follow a source-sink evolution model; the environment is the source of many lineages, some of them capable of adaptation to the human body. Some lineages may adapt to humans and go through reductive evolution in which some genes are lost. The understanding of this process may be critical to implement better methods to control outbreaks in hospitals. https://revistas.usfq.edu.ec/index.php/avances/article/view/2225Pseudomonas aeruginosahost adaptationevolutionopportunistic |
| spellingShingle | Gabriela Vasco Gabriel Trueba Pseudomonas aeruginosa transition from environmental generalist to human pathogen ACI Avances en Ciencias e Ingenierías Pseudomonas aeruginosa host adaptation evolution opportunistic |
| title | Pseudomonas aeruginosa transition from environmental generalist to human pathogen |
| title_full | Pseudomonas aeruginosa transition from environmental generalist to human pathogen |
| title_fullStr | Pseudomonas aeruginosa transition from environmental generalist to human pathogen |
| title_full_unstemmed | Pseudomonas aeruginosa transition from environmental generalist to human pathogen |
| title_short | Pseudomonas aeruginosa transition from environmental generalist to human pathogen |
| title_sort | pseudomonas aeruginosa transition from environmental generalist to human pathogen |
| topic | Pseudomonas aeruginosa host adaptation evolution opportunistic |
| url | https://revistas.usfq.edu.ec/index.php/avances/article/view/2225 |
| work_keys_str_mv | AT gabrielavasco pseudomonasaeruginosatransitionfromenvironmentalgeneralisttohumanpathogen AT gabrieltrueba pseudomonasaeruginosatransitionfromenvironmentalgeneralisttohumanpathogen |