2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective study
Abstract Aims The evidence supporting the efficacy of dietary preventive therapy in migraine is rising, particularly regarding the ketogenic diet. However, less evidence exists for the Low-Glycemic Index Diet and the 2:1 KD. This retrospective single-center real-life study aims to evaluate the effic...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-07-01
|
| Series: | The Journal of Headache and Pain |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s10194-023-01635-9 |
| _version_ | 1797769396860485632 |
|---|---|
| author | Yan Tereshko Simone Dal Bello Cherubino Di Lorenzo Sara Pez Alice Pittino Roberto Sartor Francesca Filippi Christian Lettieri Enrico Belgrado Riccardo Garbo Giovanni Merlino Gian Luigi Gigli Mariarosaria Valente |
| author_facet | Yan Tereshko Simone Dal Bello Cherubino Di Lorenzo Sara Pez Alice Pittino Roberto Sartor Francesca Filippi Christian Lettieri Enrico Belgrado Riccardo Garbo Giovanni Merlino Gian Luigi Gigli Mariarosaria Valente |
| author_sort | Yan Tereshko |
| collection | DOAJ |
| description | Abstract Aims The evidence supporting the efficacy of dietary preventive therapy in migraine is rising, particularly regarding the ketogenic diet. However, less evidence exists for the Low-Glycemic Index Diet and the 2:1 KD. This retrospective single-center real-life study aims to evaluate the efficacy of a 2:1 ketogenic diet and a Low-Glycemic-index Diet in chronic and high-frequency episodic migraine. Methods Sixty patients with high-frequency episodic and chronic migraine were treated with either a Low-Glycemic-index diet (39 patients) or a 2:1 (21 patients) ketogenic diet for three months. We collected data on the migraine frequency and intensity and the MIDAS and HIT-6 scores through the headache diary. Anthropometric measurements (BMI, fat mass, free fat mass, and weight) were also collected and analyzed similarly. Data obtained at the baseline and after three months of each diet were compared. Results Migraine intensity, frequency, MIDAS and HIT-6 scores, fat mass, weight, and BMI improved in both diet groups. Conclusions Both diets are effective in reducing migraine symptoms and migraine-related disability. |
| first_indexed | 2024-03-12T21:08:27Z |
| format | Article |
| id | doaj.art-d68b208d039146ce9db8e24725e0e48f |
| institution | Directory Open Access Journal |
| issn | 1129-2377 |
| language | English |
| last_indexed | 2024-03-12T21:08:27Z |
| publishDate | 2023-07-01 |
| publisher | BMC |
| record_format | Article |
| series | The Journal of Headache and Pain |
| spelling | doaj.art-d68b208d039146ce9db8e24725e0e48f2023-07-30T11:21:02ZengBMCThe Journal of Headache and Pain1129-23772023-07-012411810.1186/s10194-023-01635-92:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective studyYan Tereshko0Simone Dal Bello1Cherubino Di Lorenzo2Sara Pez3Alice Pittino4Roberto Sartor5Francesca Filippi6Christian Lettieri7Enrico Belgrado8Riccardo Garbo9Giovanni Merlino10Gian Luigi Gigli11Mariarosaria Valente12Clinical Neurology Unit, Udine University HospitalClinical Neurology Unit, Udine University HospitalDepartment of Medico-Surgical sciences and Biotechnologies, Sapienza University of Rome Polo PontinoClinical Neurology Unit, Udine University HospitalClinical Neurology Unit, Udine University HospitalClinical Neurology Unit, Udine University HospitalClinical Neurology Unit, Udine University HospitalClinical Neurology Unit, Udine University HospitalNeurology Unit, Udine University HospitalNeurology Unit, Hospital of GoriziaClinical Neurology Unit, Udine University HospitalDepartment of Medicine (DAME), University of UdineClinical Neurology Unit, Udine University HospitalAbstract Aims The evidence supporting the efficacy of dietary preventive therapy in migraine is rising, particularly regarding the ketogenic diet. However, less evidence exists for the Low-Glycemic Index Diet and the 2:1 KD. This retrospective single-center real-life study aims to evaluate the efficacy of a 2:1 ketogenic diet and a Low-Glycemic-index Diet in chronic and high-frequency episodic migraine. Methods Sixty patients with high-frequency episodic and chronic migraine were treated with either a Low-Glycemic-index diet (39 patients) or a 2:1 (21 patients) ketogenic diet for three months. We collected data on the migraine frequency and intensity and the MIDAS and HIT-6 scores through the headache diary. Anthropometric measurements (BMI, fat mass, free fat mass, and weight) were also collected and analyzed similarly. Data obtained at the baseline and after three months of each diet were compared. Results Migraine intensity, frequency, MIDAS and HIT-6 scores, fat mass, weight, and BMI improved in both diet groups. Conclusions Both diets are effective in reducing migraine symptoms and migraine-related disability.https://doi.org/10.1186/s10194-023-01635-9Ketogenic dietMigraineHeadacheMigraine prophylaxisLow-glycemic index diet |
| spellingShingle | Yan Tereshko Simone Dal Bello Cherubino Di Lorenzo Sara Pez Alice Pittino Roberto Sartor Francesca Filippi Christian Lettieri Enrico Belgrado Riccardo Garbo Giovanni Merlino Gian Luigi Gigli Mariarosaria Valente 2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective study The Journal of Headache and Pain Ketogenic diet Migraine Headache Migraine prophylaxis Low-glycemic index diet |
| title | 2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective study |
| title_full | 2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective study |
| title_fullStr | 2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective study |
| title_full_unstemmed | 2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective study |
| title_short | 2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective study |
| title_sort | 2 1 ketogenic diet and low glycemic index diet for the treatment of chronic and episodic migraine a single center real life retrospective study |
| topic | Ketogenic diet Migraine Headache Migraine prophylaxis Low-glycemic index diet |
| url | https://doi.org/10.1186/s10194-023-01635-9 |
| work_keys_str_mv | AT yantereshko 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT simonedalbello 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT cherubinodilorenzo 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT sarapez 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT alicepittino 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT robertosartor 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT francescafilippi 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT christianlettieri 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT enricobelgrado 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT riccardogarbo 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT giovannimerlino 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT gianluigigigli 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy AT mariarosariavalente 21ketogenicdietandlowglycemicindexdietforthetreatmentofchronicandepisodicmigraineasinglecenterrealliferetrospectivestudy |