Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc
Morphogens disperse to pattern tissues and control their growth during development, allowing for the specification of multiple fates across space. Here the authors block dispersal of a morphogen Dpp (BMP2/4) and show that the requirement for Dpp dispersal is much lower than previously thought.
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2021-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-26726-6 |
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author | Shinya Matsuda Jonas V. Schaefer Yusuke Mii Yutaro Hori Dimitri Bieli Masanori Taira Andreas Plückthun Markus Affolter |
author_facet | Shinya Matsuda Jonas V. Schaefer Yusuke Mii Yutaro Hori Dimitri Bieli Masanori Taira Andreas Plückthun Markus Affolter |
author_sort | Shinya Matsuda |
collection | DOAJ |
description | Morphogens disperse to pattern tissues and control their growth during development, allowing for the specification of multiple fates across space. Here the authors block dispersal of a morphogen Dpp (BMP2/4) and show that the requirement for Dpp dispersal is much lower than previously thought. |
first_indexed | 2024-04-11T20:50:29Z |
format | Article |
id | doaj.art-d69076491bb840b2a2706526450836a4 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-11T20:50:29Z |
publishDate | 2021-11-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-d69076491bb840b2a2706526450836a42022-12-22T04:03:52ZengNature PortfolioNature Communications2041-17232021-11-0112111810.1038/s41467-021-26726-6Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing discShinya Matsuda0Jonas V. Schaefer1Yusuke Mii2Yutaro Hori3Dimitri Bieli4Masanori Taira5Andreas Plückthun6Markus Affolter7Biozentrum, University of BaselDepartment of Biochemistry, University of ZurichNational Institute for Basic Biology and Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural SciencesInstitute for Quantitative Biosciences, The University of TokyoBiozentrum, University of BaselDepartment of Biological Sciences, Graduate School of Science, The University of TokyoDepartment of Biochemistry, University of ZurichBiozentrum, University of BaselMorphogens disperse to pattern tissues and control their growth during development, allowing for the specification of multiple fates across space. Here the authors block dispersal of a morphogen Dpp (BMP2/4) and show that the requirement for Dpp dispersal is much lower than previously thought.https://doi.org/10.1038/s41467-021-26726-6 |
spellingShingle | Shinya Matsuda Jonas V. Schaefer Yusuke Mii Yutaro Hori Dimitri Bieli Masanori Taira Andreas Plückthun Markus Affolter Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc Nature Communications |
title | Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc |
title_full | Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc |
title_fullStr | Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc |
title_full_unstemmed | Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc |
title_short | Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc |
title_sort | asymmetric requirement of dpp bmp morphogen dispersal in the drosophila wing disc |
url | https://doi.org/10.1038/s41467-021-26726-6 |
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