The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine
UHPLC-HRMS (ultra-high-performance liquid chromatography-high resolution mass spectrometry) is a new technique that unifies the application of UHPLC with HRMS. Because of the high sensitivity and good separation ability of UHPLC and the sensitivity of HRMS, this technique has been widely used for st...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.922488/full |
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| author | Jieyao Ma Jieyao Ma Kailin Li Silin Shi Jian Li Sunv Tang LiangHong Liu LiangHong Liu |
| author_facet | Jieyao Ma Jieyao Ma Kailin Li Silin Shi Jian Li Sunv Tang LiangHong Liu LiangHong Liu |
| author_sort | Jieyao Ma |
| collection | DOAJ |
| description | UHPLC-HRMS (ultra-high-performance liquid chromatography-high resolution mass spectrometry) is a new technique that unifies the application of UHPLC with HRMS. Because of the high sensitivity and good separation ability of UHPLC and the sensitivity of HRMS, this technique has been widely used for structure identification, quantitative determination, fingerprint analysis, and elucidation of the mechanisms of action of traditional Chinese medicines (TCMs) in recent years. This review mainly outlines the advantages of using UHPLC-HRMS and provides a survey of the research advances on UHPLC-HRMS for the quality control of TCMs. |
| first_indexed | 2024-12-12T07:28:30Z |
| format | Article |
| id | doaj.art-d6907f7dbbae4724b988203b8ca7b81d |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-12-12T07:28:30Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-d6907f7dbbae4724b988203b8ca7b81d2022-12-22T00:33:05ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122022-06-011310.3389/fphar.2022.922488922488The Application of UHPLC-HRMS for Quality Control of Traditional Chinese MedicineJieyao Ma0Jieyao Ma1Kailin Li2Silin Shi3Jian Li4Sunv Tang5LiangHong Liu6LiangHong Liu7School of Pharmaceutical Sciences, Hunan Province Key Laboratory for Antibody-Based Drug and Intelligent Delivery System, Hunan University of Medicine, Huaihua, ChinaHunan Provincial Key Laboratory of Dong Medicine, Hunan University of Medicine, Huaihua, ChinaSchool of Pharmaceutical Sciences, Hunan Province Key Laboratory for Antibody-Based Drug and Intelligent Delivery System, Hunan University of Medicine, Huaihua, ChinaSchool of Pharmaceutical Sciences, Hunan Province Key Laboratory for Antibody-Based Drug and Intelligent Delivery System, Hunan University of Medicine, Huaihua, ChinaSchool of Pharmaceutical Sciences, Hunan Province Key Laboratory for Antibody-Based Drug and Intelligent Delivery System, Hunan University of Medicine, Huaihua, ChinaSchool of Pharmaceutical Sciences, Hunan Province Key Laboratory for Antibody-Based Drug and Intelligent Delivery System, Hunan University of Medicine, Huaihua, ChinaSchool of Pharmaceutical Sciences, Hunan Province Key Laboratory for Antibody-Based Drug and Intelligent Delivery System, Hunan University of Medicine, Huaihua, ChinaHunan Provincial Key Laboratory of Dong Medicine, Hunan University of Medicine, Huaihua, ChinaUHPLC-HRMS (ultra-high-performance liquid chromatography-high resolution mass spectrometry) is a new technique that unifies the application of UHPLC with HRMS. Because of the high sensitivity and good separation ability of UHPLC and the sensitivity of HRMS, this technique has been widely used for structure identification, quantitative determination, fingerprint analysis, and elucidation of the mechanisms of action of traditional Chinese medicines (TCMs) in recent years. This review mainly outlines the advantages of using UHPLC-HRMS and provides a survey of the research advances on UHPLC-HRMS for the quality control of TCMs.https://www.frontiersin.org/articles/10.3389/fphar.2022.922488/fullUHPLC-HRMStraditional Chinese medicine (TCM)structure identificationfingerprint analysisquality control |
| spellingShingle | Jieyao Ma Jieyao Ma Kailin Li Silin Shi Jian Li Sunv Tang LiangHong Liu LiangHong Liu The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine Frontiers in Pharmacology UHPLC-HRMS traditional Chinese medicine (TCM) structure identification fingerprint analysis quality control |
| title | The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine |
| title_full | The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine |
| title_fullStr | The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine |
| title_full_unstemmed | The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine |
| title_short | The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine |
| title_sort | application of uhplc hrms for quality control of traditional chinese medicine |
| topic | UHPLC-HRMS traditional Chinese medicine (TCM) structure identification fingerprint analysis quality control |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2022.922488/full |
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