TUBERCULOUS SPONDYLITIS IN ADULTS: CLINICAL AND RADIOGRAPHIC MANIFESTATIONS
The clinical and radiographic manifestations of maturity-onset tuberculous spondylitis were analyzed in 107 patients. If Mycobacterium tuberculosis (MBT) is drug resistant, the extent and degree of spinal bone destruction, the extent of abscess formation, and the rate of neurological disorders are g...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2014-10-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/289 |
| _version_ | 1826563263810240512 |
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| author | N. A. Sovetova G. Yu. Vasilyeva N. S. Solovyeva V. Yu. Zhuravlev I. A. Baulin |
| author_facet | N. A. Sovetova G. Yu. Vasilyeva N. S. Solovyeva V. Yu. Zhuravlev I. A. Baulin |
| author_sort | N. A. Sovetova |
| collection | DOAJ |
| description | The clinical and radiographic manifestations of maturity-onset tuberculous spondylitis were analyzed in 107 patients. If Mycobacterium tuberculosis (MBT) is drug resistant, the extent and degree of spinal bone destruction, the extent of abscess formation, and the rate of neurological disorders are greater than those in the MBT drug sensitivity group; however, the significant difference concerns only the involvement of vertebral arches in destruction. The pattern and activity of a tuberculous process in the lung and the proportion of bacteria-excreting persons with drug resistance in MBT significantly exceed those with drug sensitivity. All the patients were operated on; the diagnosis was histologically verified in 100% of cases; the postoperative specimens exhibited MBT culture in 72.9%; the polymerase chain reaction was positive n 98.9%. Bacteriological and molecular genetic studies established multiple drug resistance in 73.4%, polyresistance in 17.3%, and monoresistance in 9.3%. |
| first_indexed | 2024-03-12T18:44:10Z |
| format | Article |
| id | doaj.art-d69110ea8c45416fac40e2bdfc5c0579 |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2025-03-14T10:01:11Z |
| publishDate | 2014-10-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-d69110ea8c45416fac40e2bdfc5c05792025-03-02T11:22:20ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062014-10-01010333710.21292/2075-1230-2014-0-10-33-37289TUBERCULOUS SPONDYLITIS IN ADULTS: CLINICAL AND RADIOGRAPHIC MANIFESTATIONSN. A. Sovetova0G. Yu. Vasilyeva1N. S. Solovyeva2V. Yu. Zhuravlev3I. A. Baulin4ФГБУ «Санкт-Петербургский научно-исследовательский институт фтизиопульмонологии» Минздрава РоссииФГБУ «Санкт-Петербургский научно-исследовательский институт фтизиопульмонологии» Минздрава РоссииФГБУ «Санкт-Петербургский научно-исследовательский институт фтизиопульмонологии» Минздрава РоссииФГБУ «Санкт-Петербургский научно-исследовательский институт фтизиопульмонологии» Минздрава РоссииФГБУ «Санкт-Петербургский научно-исследовательский институт фтизиопульмонологии» Минздрава РоссииThe clinical and radiographic manifestations of maturity-onset tuberculous spondylitis were analyzed in 107 patients. If Mycobacterium tuberculosis (MBT) is drug resistant, the extent and degree of spinal bone destruction, the extent of abscess formation, and the rate of neurological disorders are greater than those in the MBT drug sensitivity group; however, the significant difference concerns only the involvement of vertebral arches in destruction. The pattern and activity of a tuberculous process in the lung and the proportion of bacteria-excreting persons with drug resistance in MBT significantly exceed those with drug sensitivity. All the patients were operated on; the diagnosis was histologically verified in 100% of cases; the postoperative specimens exhibited MBT culture in 72.9%; the polymerase chain reaction was positive n 98.9%. Bacteriological and molecular genetic studies established multiple drug resistance in 73.4%, polyresistance in 17.3%, and monoresistance in 9.3%.https://www.tibl-journal.com/jour/article/view/289tuberculosisosteoarticular tuberculosis in adultstuberculous spondylitisclinical and radiographic manifestationsdrug resistance in mycobacterium tuberculosis |
| spellingShingle | N. A. Sovetova G. Yu. Vasilyeva N. S. Solovyeva V. Yu. Zhuravlev I. A. Baulin TUBERCULOUS SPONDYLITIS IN ADULTS: CLINICAL AND RADIOGRAPHIC MANIFESTATIONS Туберкулез и болезни лёгких tuberculosis osteoarticular tuberculosis in adults tuberculous spondylitis clinical and radiographic manifestations drug resistance in mycobacterium tuberculosis |
| title | TUBERCULOUS SPONDYLITIS IN ADULTS: CLINICAL AND RADIOGRAPHIC MANIFESTATIONS |
| title_full | TUBERCULOUS SPONDYLITIS IN ADULTS: CLINICAL AND RADIOGRAPHIC MANIFESTATIONS |
| title_fullStr | TUBERCULOUS SPONDYLITIS IN ADULTS: CLINICAL AND RADIOGRAPHIC MANIFESTATIONS |
| title_full_unstemmed | TUBERCULOUS SPONDYLITIS IN ADULTS: CLINICAL AND RADIOGRAPHIC MANIFESTATIONS |
| title_short | TUBERCULOUS SPONDYLITIS IN ADULTS: CLINICAL AND RADIOGRAPHIC MANIFESTATIONS |
| title_sort | tuberculous spondylitis in adults clinical and radiographic manifestations |
| topic | tuberculosis osteoarticular tuberculosis in adults tuberculous spondylitis clinical and radiographic manifestations drug resistance in mycobacterium tuberculosis |
| url | https://www.tibl-journal.com/jour/article/view/289 |
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