AMPK‐upregulated microRNA‐708 plays as a suppressor of cellular senescence and aging via downregulating disabled‐2 and mTORC1 activation

AMPK‐upregulated microRNA‐708 plays as a suppressor of cellular senescence and aging via downregulating disabled‐2 and mTORC1 activation

Abstract Senescence‐associated microRNAs (SA‐miRNAs) are important molecules for aging regulation. While many aging‐promoting SA‐miRNAs have been identified, confirmed aging‐suppressive SA‐miRNAs are rare, that impeded our full understanding on aging regulation. In this study, we verified that miR‐7...

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Bibliographic Details
Main Authors: Jian Zhang, Hui Gong, Tingting Zhao, Weitong Xu, Honghan Chen, Tiepeng Li, Yu Yang, Ming Yang, Ning Huang, Chuhui Gong, Fangfang Wang, Cuiying Zhang, Jin Liu, Hengyi Xiao
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:MedComm
Subjects:
aging
AMP‐activated protein kinase (AMPK)
Disabled 2 (DAB2)
miR‐708
mammalian traget of rapamycin coplex 1 (mTORC1)
Online Access:https://doi.org/10.1002/mco2.475

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