Early Dynamics of Quantitative <i>SEPT9</i> and <i>SHOX2</i> Methylation in Circulating Cell-Free Plasma DNA during Prostate Biopsy for Prostate Cancer Diagnosis

Early Dynamics of Quantitative <i>SEPT9</i> and <i>SHOX2</i> Methylation in Circulating Cell-Free Plasma DNA during Prostate Biopsy for Prostate Cancer Diagnosis

Background: The methylation status of <i>Septin 9</i> (<i>SEPT9</i>) and <i>short stature homeobox 2</i> (<i>SHOX2</i>) in circulating cell-free DNA (ccfDNA) are validated pan-cancer biomarkers. The present proof-of-concept study aimed to investigate t...

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Bibliographic Details
Main Authors: Philipp Krausewitz, Niklas Kluemper, Ayk-Peter Richter, Thomas Büttner, Glen Kristiansen, Manuel Ritter, Jörg Ellinger
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
prostate cancer
biomarker
methylation
circulating cell-free DNA
<i>SHOX2</i>
<i>SEPT9</i>
Online Access:https://www.mdpi.com/2072-6694/14/18/4355

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