Evaluation of neuropsychiatric symptoms in patients with multiple sclerosis
Purpose: The aim of this study was to comprehensively assess the neurophyschiatric symptoms of multiple sclerosis (MS) such as apathy and pseudobulbar affect and their correlation with other concomitant factors. Materials and Methods: Montreal Cognitive Assessment (MoCA), Apathy Evaluation Scale (AE...
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| Format: | Article |
| Language: | English |
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Cukurova University
2022-03-01
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| Series: | Cukurova Medical Journal |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/2061785 |
| _version_ | 1797908077381419008 |
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| author | İpek Gungor Dogan Didem Celik Ozlem Totuk Serkan Demir Ozge Gonul Oner |
| author_facet | İpek Gungor Dogan Didem Celik Ozlem Totuk Serkan Demir Ozge Gonul Oner |
| author_sort | İpek Gungor Dogan |
| collection | DOAJ |
| description | Purpose: The aim of this study was to comprehensively assess the neurophyschiatric symptoms of multiple sclerosis (MS) such as apathy and pseudobulbar affect and their correlation with other concomitant factors.
Materials and Methods: Montreal Cognitive Assessment (MoCA), Apathy Evaluation Scale (AES), Fatigue severity scale (FSS), Center for Neurologic Study-Lability Scale (CNS-LS), Beck Depression Inventory (BDI) are applied to 258 MS patients. Correlation and regression analysis are conducted between scales and other possible causers.
Results: 53.6% of the patients have psuedobulbar affect, 76.2% of patient population have fatigue. Pseudobulbar affect had positive correlation with fatigue and also depression while apathy negatively correlate with pseudobulbar affect or fatigue. Additionally, apathy and depression correlated negatively. There was no relation between cognition and depression and/or disease duration and/or other scales’ scores.
Conclusion: Pseudobulbar affect and apathy are quite common symptoms in MS patients, that are cross-cutting issues. Also, apathy may be an independent neuropyschiatric symptom of MS that need to be approached separately. |
| first_indexed | 2024-04-10T10:46:58Z |
| format | Article |
| id | doaj.art-d69609bb6c7041baac33b443bf801c1a |
| institution | Directory Open Access Journal |
| issn | 2602-3040 |
| language | English |
| last_indexed | 2024-04-10T10:46:58Z |
| publishDate | 2022-03-01 |
| publisher | Cukurova University |
| record_format | Article |
| series | Cukurova Medical Journal |
| spelling | doaj.art-d69609bb6c7041baac33b443bf801c1a2023-02-15T16:20:17ZengCukurova UniversityCukurova Medical Journal2602-30402022-03-0147120821810.17826/cumj.101863248Evaluation of neuropsychiatric symptoms in patients with multiple sclerosisİpek Gungor Dogan0Didem Celik1Ozlem Totuk2Serkan Demir3Ozge Gonul Oner4SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL SANCAKTEPE ŞEHİR PROF. DR. İLHAN VARANK SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÖROLOJİ ANABİLİM DALISAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL SANCAKTEPE ŞEHİR PROF. DR. İLHAN VARANK SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÖROLOJİ ANABİLİM DALISAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL SANCAKTEPE ŞEHİR PROF. DR. İLHAN VARANK SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÖROLOJİ ANABİLİM DALISAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL SANCAKTEPE ŞEHİR PROF. DR. İLHAN VARANK SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÖROLOJİ ANABİLİM DALISAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL SANCAKTEPE ŞEHİR PROF. DR. İLHAN VARANK SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÖROLOJİ ANABİLİM DALIPurpose: The aim of this study was to comprehensively assess the neurophyschiatric symptoms of multiple sclerosis (MS) such as apathy and pseudobulbar affect and their correlation with other concomitant factors. Materials and Methods: Montreal Cognitive Assessment (MoCA), Apathy Evaluation Scale (AES), Fatigue severity scale (FSS), Center for Neurologic Study-Lability Scale (CNS-LS), Beck Depression Inventory (BDI) are applied to 258 MS patients. Correlation and regression analysis are conducted between scales and other possible causers. Results: 53.6% of the patients have psuedobulbar affect, 76.2% of patient population have fatigue. Pseudobulbar affect had positive correlation with fatigue and also depression while apathy negatively correlate with pseudobulbar affect or fatigue. Additionally, apathy and depression correlated negatively. There was no relation between cognition and depression and/or disease duration and/or other scales’ scores. Conclusion: Pseudobulbar affect and apathy are quite common symptoms in MS patients, that are cross-cutting issues. Also, apathy may be an independent neuropyschiatric symptom of MS that need to be approached separately.https://dergipark.org.tr/tr/download/article-file/2061785msapathypseudobulbar affectmsapatipsödobulbar etkiler |
| spellingShingle | İpek Gungor Dogan Didem Celik Ozlem Totuk Serkan Demir Ozge Gonul Oner Evaluation of neuropsychiatric symptoms in patients with multiple sclerosis Cukurova Medical Journal ms apathy pseudobulbar affect ms apati psödobulbar etkiler |
| title | Evaluation of neuropsychiatric symptoms in patients with multiple sclerosis |
| title_full | Evaluation of neuropsychiatric symptoms in patients with multiple sclerosis |
| title_fullStr | Evaluation of neuropsychiatric symptoms in patients with multiple sclerosis |
| title_full_unstemmed | Evaluation of neuropsychiatric symptoms in patients with multiple sclerosis |
| title_short | Evaluation of neuropsychiatric symptoms in patients with multiple sclerosis |
| title_sort | evaluation of neuropsychiatric symptoms in patients with multiple sclerosis |
| topic | ms apathy pseudobulbar affect ms apati psödobulbar etkiler |
| url | https://dergipark.org.tr/tr/download/article-file/2061785 |
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