Neurofilament light chain in the vitreous humor of the eye

Neurofilament light chain in the vitreous humor of the eye

Abstract Background Neurofilament light chain (NfL) is a promising biomarker of neurodegeneration in the cerebrospinal fluid and blood. This study investigated the presence of NfL in the vitreous humor and its associations with amyloid beta, tau, inflammatory cytokines and vascular proteins, apolipo...

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Main Authors: Manju L. Subramanian, Viha Vig, Jaeyoon Chung, Marissa G. Fiorello, Weiming Xia, Henrik Zetterberg, Kaj Blennow, Madeleine Zetterberg, Farah Shareef, Nicole H. Siegel, Steven Ness, Gyungah R. Jun, Thor D. Stein
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Vitreous humor
Neuro-filament light chain
Ocular biomarkers
Amyloid beta
Tau
Online Access:http://link.springer.com/article/10.1186/s13195-020-00677-4

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