Developmental Accumulation of Gene Body and Transposon Non-CpG Methylation in the Zebrafish Brain

DNA methylation predominantly occurs at CG dinucleotides in vertebrate genomes; however, non-CG methylation (mCH) is also detectable in vertebrate tissues, most notably in the nervous system. In mammals it is well established that mCH is targeted to CAC trinucleotides by DNMT3A during nervous system...

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Bibliographic Details
Main Authors: Samuel E. Ross, Daniel Hesselson, Ozren Bogdanovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.643603/full

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