Rare case of proximal coronary plaque regression after distal arterial grafting
The metabolically active endothelium of arterial grafts is reported to slow the atherosclerotic process in the distal coronary territories to which they are grafted with improved patency. The literature on arterial grafting causing proximal plaque regression is scant. We report here a case of proxim...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2016-09-01
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| Series: | Indian Heart Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483215002874 |
| _version_ | 1819095221475999744 |
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| author | George Jose Valooran Shiv Kumar Nair Krishnan Chandrasekharan |
| author_facet | George Jose Valooran Shiv Kumar Nair Krishnan Chandrasekharan |
| author_sort | George Jose Valooran |
| collection | DOAJ |
| description | The metabolically active endothelium of arterial grafts is reported to slow the atherosclerotic process in the distal coronary territories to which they are grafted with improved patency. The literature on arterial grafting causing proximal plaque regression is scant. We report here a case of proximal left anterior descending artery (LAD) plaque regression following distal arterial grafting with a left internal mammary arterial (LIMA) graft to LAD. This rarely documented regression resulted in “stringing” of the arterial graft, while there was a significant progression of atherosclerotic disease in the right coronary with patent venous graft and de novo lesion in circumflex territory necessitating percutaneous coronary intervention, in spite of aggressive medical therapy. The dichotomous progression of disease in two out of three coronary arterial systems and regression of the proximal plaque in LAD grafted with LIMA 12 years ago suggests the protective effect of arterial grafting in reversing the atherosclerotic process. |
| first_indexed | 2024-12-21T23:39:51Z |
| format | Article |
| id | doaj.art-d697d35090ea437488c766b6f9ecd44a |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-12-21T23:39:51Z |
| publishDate | 2016-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-d697d35090ea437488c766b6f9ecd44a2022-12-21T18:46:15ZengElsevierIndian Heart Journal0019-48322016-09-0168S2S47S5010.1016/j.ihj.2015.07.029Rare case of proximal coronary plaque regression after distal arterial graftingGeorge Jose ValooranShiv Kumar NairKrishnan ChandrasekharanThe metabolically active endothelium of arterial grafts is reported to slow the atherosclerotic process in the distal coronary territories to which they are grafted with improved patency. The literature on arterial grafting causing proximal plaque regression is scant. We report here a case of proximal left anterior descending artery (LAD) plaque regression following distal arterial grafting with a left internal mammary arterial (LIMA) graft to LAD. This rarely documented regression resulted in “stringing” of the arterial graft, while there was a significant progression of atherosclerotic disease in the right coronary with patent venous graft and de novo lesion in circumflex territory necessitating percutaneous coronary intervention, in spite of aggressive medical therapy. The dichotomous progression of disease in two out of three coronary arterial systems and regression of the proximal plaque in LAD grafted with LIMA 12 years ago suggests the protective effect of arterial grafting in reversing the atherosclerotic process.http://www.sciencedirect.com/science/article/pii/S0019483215002874Coronary artery bypass graftingInternal mammary arteryCoronary plaqueArterial graftStatins |
| spellingShingle | George Jose Valooran Shiv Kumar Nair Krishnan Chandrasekharan Rare case of proximal coronary plaque regression after distal arterial grafting Indian Heart Journal Coronary artery bypass grafting Internal mammary artery Coronary plaque Arterial graft Statins |
| title | Rare case of proximal coronary plaque regression after distal arterial grafting |
| title_full | Rare case of proximal coronary plaque regression after distal arterial grafting |
| title_fullStr | Rare case of proximal coronary plaque regression after distal arterial grafting |
| title_full_unstemmed | Rare case of proximal coronary plaque regression after distal arterial grafting |
| title_short | Rare case of proximal coronary plaque regression after distal arterial grafting |
| title_sort | rare case of proximal coronary plaque regression after distal arterial grafting |
| topic | Coronary artery bypass grafting Internal mammary artery Coronary plaque Arterial graft Statins |
| url | http://www.sciencedirect.com/science/article/pii/S0019483215002874 |
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