Image Scanning Microscopy to Investigate Polycomb Protein Colocalization onto Chromatin

Image Scanning Microscopy to Investigate Polycomb Protein Colocalization onto Chromatin

Super-resolution microscopy has been recently applied to understand the 3D topology of chromatin at an intermediated genomic scale (kilobases to a few megabases), as this corresponds to a sub-diffraction spatial scale crucial for the regulation of gene transcription. In this context, polycomb protei...

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Bibliographic Details
Main Authors: Irene Nepita, Simonluca Piazza, Martina Ruglioni, Sofia Cristiani, Emanuele Bosurgi, Tiziano Salvadori, Giuseppe Vicidomini, Alberto Diaspro, Marco Castello, Paolo Bianchini, Barbara Storti, Ranieri Bizzarri
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Applied Sciences
Subjects:
chromatin topology
polycomb proteins
PRC1
PRC2
BMI1
EZH2
Online Access:https://www.mdpi.com/2076-3417/13/3/1556

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