AAV-compatible optogenetic tools for activating endogenous calcium channels in vivo

AAV-compatible optogenetic tools for activating endogenous calcium channels in vivo

Abstract Calcium ions (Ca2+) play pivotal roles in regulating diverse brain functions, including cognition, emotion, locomotion, and learning and memory. These functions are intricately regulated by a variety of Ca2+-dependent cellular processes, encompassing synaptic plasticity, neuro/gliotransmitt...

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Bibliographic Details
Main Authors: Yeon Hee Kook, Hyoin Lee, Jinsu Lee, Yeonji Jeong, Jaerang Rho, Won Do Heo, Sangkyu Lee
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Molecular Brain
Subjects:
Calcium ion
Optogenetics
Adeno-associated virus
Neurons
Glial cells
Online Access:https://doi.org/10.1186/s13041-023-01061-7

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