The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders
Bacteria, as well as eukaryotes, principally fungi, of the upper respiratory tract play key roles in the etiopathogenesis of respiratory diseases, whereas the potential role of archaea remains poorly understood. In this review, we discuss the contribution of all three domains of cellular life to hum...
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MDPI AG
2022-04-01
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| Online Access: | https://www.mdpi.com/2073-4409/11/8/1287 |
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| author | Carolin Baehren Eleni Buedding Aliyah Bellm Frank Schult Anton Pembaur Stefan Wirth Anja Ehrhardt Friedrich Paulsen Jan Postberg Malik Aydin |
| author_facet | Carolin Baehren Eleni Buedding Aliyah Bellm Frank Schult Anton Pembaur Stefan Wirth Anja Ehrhardt Friedrich Paulsen Jan Postberg Malik Aydin |
| author_sort | Carolin Baehren |
| collection | DOAJ |
| description | Bacteria, as well as eukaryotes, principally fungi, of the upper respiratory tract play key roles in the etiopathogenesis of respiratory diseases, whereas the potential role of archaea remains poorly understood. In this review, we discuss the contribution of all three domains of cellular life to human naso- and oropharyngeal microbiomes, i.e., bacterial microbiota, eukaryotes (mostly fungi), as well as the archaeome and their relation to respiratory and atopic disorders in infancy and adolescence. With this review, we aim to summarize state-of-the-art contributions to the field published in the last decade. In particular, we intend to build bridges between basic and clinical science. |
| first_indexed | 2024-03-09T11:02:36Z |
| format | Article |
| id | doaj.art-d6a44503b0744de5b01e1a7827a15d81 |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-09T11:02:36Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-d6a44503b0744de5b01e1a7827a15d812023-12-01T01:13:27ZengMDPI AGCells2073-44092022-04-01118128710.3390/cells11081287The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory DisordersCarolin Baehren0Eleni Buedding1Aliyah Bellm2Frank Schult3Anton Pembaur4Stefan Wirth5Anja Ehrhardt6Friedrich Paulsen7Jan Postberg8Malik Aydin9Laboratory of Experimental Pediatric Pneumology and Allergology, Center for Biomedical Education and Research, School of Life Sciences (ZBAF), Faculty of Health, Witten/Herdecke University, 58455 Witten, GermanyLaboratory of Experimental Pediatric Pneumology and Allergology, Center for Biomedical Education and Research, School of Life Sciences (ZBAF), Faculty of Health, Witten/Herdecke University, 58455 Witten, GermanyHelios Hospital Krefeld, Children’s Hospital, Teaching Hospital of RTWH University Hospital Aachen, 47805 Krefeld, GermanyCenter for Child and Adolescent Medicine, Center for Clinical and Translational Research (CCTR), Helios University Hospital Wuppertal, Witten/Herdecke University, 42283 Wuppertal, GermanyClinical Molecular Genetics and Epigenetics, Faculty of Health, Center for Biomedical Education & Research (ZBAF), Helios University Hospital Wuppertal, Witten/Herdecke University, Alfred-Herrhausen-Str. 50, 58448 Witten, GermanyCenter for Child and Adolescent Medicine, Center for Clinical and Translational Research (CCTR), Helios University Hospital Wuppertal, Witten/Herdecke University, 42283 Wuppertal, GermanyInstitute of Virology and Microbiology, Center for Biomedical Education and Research (ZBAF), Department of Human Medicine, Faculty of Health, Witten/Herdecke University, 58453 Witten, GermanyInstitute of Functional and Clinical Anatomy, Friedrich Alexander University Erlangen-Nürnberg, 91054 Erlangen, GermanyClinical Molecular Genetics and Epigenetics, Faculty of Health, Center for Biomedical Education & Research (ZBAF), Helios University Hospital Wuppertal, Witten/Herdecke University, Alfred-Herrhausen-Str. 50, 58448 Witten, GermanyLaboratory of Experimental Pediatric Pneumology and Allergology, Center for Biomedical Education and Research, School of Life Sciences (ZBAF), Faculty of Health, Witten/Herdecke University, 58455 Witten, GermanyBacteria, as well as eukaryotes, principally fungi, of the upper respiratory tract play key roles in the etiopathogenesis of respiratory diseases, whereas the potential role of archaea remains poorly understood. In this review, we discuss the contribution of all three domains of cellular life to human naso- and oropharyngeal microbiomes, i.e., bacterial microbiota, eukaryotes (mostly fungi), as well as the archaeome and their relation to respiratory and atopic disorders in infancy and adolescence. With this review, we aim to summarize state-of-the-art contributions to the field published in the last decade. In particular, we intend to build bridges between basic and clinical science.https://www.mdpi.com/2073-4409/11/8/1287microbiomearchaeafunginasopharynxoropharynxasthma |
| spellingShingle | Carolin Baehren Eleni Buedding Aliyah Bellm Frank Schult Anton Pembaur Stefan Wirth Anja Ehrhardt Friedrich Paulsen Jan Postberg Malik Aydin The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders Cells microbiome archaea fungi nasopharynx oropharynx asthma |
| title | The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders |
| title_full | The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders |
| title_fullStr | The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders |
| title_full_unstemmed | The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders |
| title_short | The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders |
| title_sort | relevance of the bacterial microbiome archaeome and mycobiome in pediatric asthma and respiratory disorders |
| topic | microbiome archaea fungi nasopharynx oropharynx asthma |
| url | https://www.mdpi.com/2073-4409/11/8/1287 |
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