The identification and verification of hub genes associated with pulmonary arterial hypertension using weighted gene co-expression network analysis

The identification and verification of hub genes associated with pulmonary arterial hypertension using weighted gene co-expression network analysis

Abstract Background Pulmonary arterial hypertension (PAH) is characterized by a progressive increase in pulmonary vascular resistance and pulmonary arterial pressure, with complex etiology, difficult treatment and poor prognosis. The objective of this study was to investigate the potential biomarker...

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Bibliographic Details
Main Authors: Weibin Wu, Ai Chen, Siming Lin, Qiuran Wang, Guili Lian, Li Luo, Liangdi Xie
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Pulmonary Medicine
Subjects:
Hub genes
Pulmonary arterial hypertension
WGCNA
GSEA
Bioinformatics
Online Access:https://doi.org/10.1186/s12890-022-02275-6

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