Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses

Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses

The eradication of tumor cells requires communication to and signaling by cells of the immune system. Natural killer (NK) cells are essential tumor-killing effector cells of the innate immune system; however, little is known about whether or how other immune cells recognize tumor cells to assist NK...

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Bibliographic Details
Main Authors: Shiho Chiba, Hiroaki Ikushima, Hiroshi Ueki, Hideyuki Yanai, Yoshitaka Kimura, Sho Hangai, Junko Nishio, Hideo Negishi, Tomohiko Tamura, Shinobu Saijo, Yoichiro Iwakura, Tadatsugu Taniguchi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-08-01
Series:eLife
Subjects:
innate immunity
Dectin-1
NK cell
IRF
Online Access:https://elifesciences.org/articles/04177

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