Relationship between EGFR Promoter Region Methylation and Secondary Resistance Which may be Induced by Gefitinib

Relationship between EGFR Promoter Region Methylation and Secondary Resistance Which may be Induced by Gefitinib

Background and objective Nowadays the secondary resistance of gefitinib in the treatment of lung adenocarcinoma is an outstanding problem. This research is to explore whether the gefitinib secondary resistance can be induced by gefitinib, to explore whether epidermal growth factor receptor (EGFR) pr...

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Bibliographic Details
Main Authors: Qilong WANG, Min LI, Chengping HU
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2015-04-01
Series:Chinese Journal of Lung Cancer
Subjects:
Lung neoplasms
Tyrosine kinase inhibitor
Secondary resistance
Epidemal growth factor receptor
Methylation
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2015.04.04

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