Ebselen: A promising therapy protecting cardiomyocytes from excess iron in iron-overloaded thalassemia patients
Iron-overload-associated cardiomyopathy has been one of the primary causes of mortality in thalassemia patients with iron burden. There is growing evidence citing the beneficial effects of ebselen as an antioxidant selectively blocking the divalent metal transporter 1 (DMT-1) to deter iron ingress i...
Main Authors: | Ghazaiean Mobin, Aliasgharian Aily, Karami Hossein, Darvishi-Khezri Hadi |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2023-07-01
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Series: | Open Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1515/med-2023-0733 |
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