Ebselen: A promising therapy protecting cardiomyocytes from excess iron in iron-overloaded thalassemia patients

Iron-overload-associated cardiomyopathy has been one of the primary causes of mortality in thalassemia patients with iron burden. There is growing evidence citing the beneficial effects of ebselen as an antioxidant selectively blocking the divalent metal transporter 1 (DMT-1) to deter iron ingress i...

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Bibliographic Details
Main Authors: Ghazaiean Mobin, Aliasgharian Aily, Karami Hossein, Darvishi-Khezri Hadi
Format: Article
Language:English
Published: De Gruyter 2023-07-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2023-0733

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